Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12499833 | 1.00 | MEN1 (0.51) | MEN1KMT2AMAPTEPHX1MAPK8 | |
| SCHEMBL12500066 | 0.84 | EPHX1 (0.49) | MEN1KMT2AMAPTEPHX1MAPK8 | |
| SCHEMBL12500069 | 0.84 | EPHX1 (0.49) | MEN1KMT2AMAPTEPHX1MAPK8 | |
| SCHEMBL12498763 | 0.84 | CTBP2 (0.50) | MEN1KMT2AMAPK8ALDH1A1 | |
| SCHEMBL12498765 | 0.84 | CTBP2 (0.50) | MEN1KMT2AMAPK8ALDH1A1 | |
| SCHEMBL12498668 | 0.83 | PIK3CA (0.42) | MAPK8MAOBTAAR1IDO1 | |
| SCHEMBL12498667 | 0.83 | PIK3CA (0.42) | MAPK8MAOBTAAR1IDO1 | |
| SCHEMBL30496803 | 0.78 | EPHX1 (0.59) | MEN1KMT2AMAPTEPHX1MAPK8 | |
| SCHEMBL966493 | 0.78 | EPHX1 (0.59) | MEN1KMT2AMAPTEPHX1MAPK8 | |
| SCHEMBL12499754 | 0.77 | KMT2A (0.40) | MEN1KMT2AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012103071-A2 | COMPOUNDS AND COMPOSITIONS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-08-02 | — | — | WO | disclosed |