Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.30 |
| ▸ | KDR | P35968 | 2/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1478316 | 0.83 | KDM4E (0.39) | KDM4EPKMRCE1KLKB1ALDH1A1 | |
| SCHEMBL11028213 | 0.82 | KDM4E (0.39) | KDM4EPKMRCE1KLKB1ALDH1A1 | |
| SCHEMBL718435 | 0.81 | TAS1R3 (0.37) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1917989 | 0.81 | TAS1R3 (0.37) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1918801 | 0.81 | KDM4E (0.36) | KDM4EPKMRCE1KLKB1ALDH1A1 | |
| SCHEMBL718750 | 0.78 | KDM4E (0.33) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL719379 | 0.78 | TAS1R3 (0.38) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11027458 | 0.78 | KDM4E (0.34) | KDM4EPKMRCE1KLKB1ALDH1A1 | |
| SCHEMBL11027454 | 0.78 | KDM4E (0.34) | KDM4EPKMRCE1KLKB1ALDH1A1 | |
| SCHEMBL718835 | 0.77 | KDM4E (0.35) | KDM4EPKMRCE1KLKB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2667717-A2 | 6-AMINO-2-SUBSTITUTED-5-VINYLSILYLPYRIMIDINE-4-CARBOXYLIC ACIDS AND ESTERS AND 4-AMINO-6-SUBSTITUTED-3-VINYLSILYLPYRIDINE-2-CARBOXYLIC ACIDS AND ESTERS AS HERBICIDES | Dow AgroSciences LLC (US) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012103051-A2 | 6-AMINO-2-SUBSTITUTED-5-VINYLSILYLPYRIMIDINE-4-CARBOXYLIC ACIDS AND ESTERS AND 4-AMINO-6-SUBSTITUTED-3-VINYLSILYLPYRIDINE-2-CARBOXYLIC ACIDS AND ESTERS AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2012-08-02 | — | — | WO | disclosed |