⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3767365 | 1.00 | — | — | |
| SCHEMBL29269897 | 0.79 | USP2 (0.31) | — | |
| SCHEMBL27719668 | 0.77 | — | — | |
| SCHEMBL29692256 | 0.73 | — | — | |
| SCHEMBL11428108 | 0.73 | SLC22A6 (0.31) | — | |
| SCHEMBL28292381 | 0.73 | PDE4A (0.43) | — | |
| SCHEMBL1843798 | 0.73 | PDE4A (0.43) | — | |
| SCHEMBL18825591 | 0.73 | PDE4A (0.43) | — | |
| SCHEMBL858818 | 0.73 | PDE4A (0.43) | — | |
| SCHEMBL11491528 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088564-A1 | SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS | DSM IP ASSETS B.V. (NL) | 2017-03-30 | — | — | US | disclosed |
| EP-2670757-B1 | SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS | DSM IP ASSETS BV (NL) | 2015-05-27 | — | — | EP | disclosed |
| US-20140135408-A1 | SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS | DSM IP ASSETS B.V. (NL) | 2014-05-15 | — | — | US | disclosed |
| EP-2670757-A1 | SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS | DSM IP Assets B.V. (NL) | 2013-12-11 | — | — | EP | disclosed |
| WO-2012104349-A1 | SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS | DSM IP ASSETS B.V. (NL) | 2012-08-09 | — | — | WO | disclosed |