Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PAM | P19021 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12504523 | 0.91 | DGKA (0.44) | DGKACES1CES2ALDH1A1LMNA | |
| SCHEMBL28425728 | 0.89 | DGKA (0.47) | DGKACES1CES2ALDH1A1LMNA | |
| SCHEMBL12504368 | 0.87 | DGKA (0.38) | DGKACES1CES2ALDH1A1LMNA | |
| SCHEMBL28416426 | 0.86 | DGKA (0.47) | DGKACES1CES2ALDH1A1LMNA | |
| SCHEMBL28423869 | 0.86 | DGKA (0.47) | DGKACES1CES2ALDH1A1LMNA | |
| SCHEMBL28416455 | 0.86 | DGKA (0.47) | DGKACES1CES2ALDH1A1LMNA | |
| SCHEMBL12504282 | 0.86 | DGKA (0.39) | DGKACES1CES2ALDH1A1LMNA | |
| SCHEMBL28422711 | 0.86 | DGKA (0.47) | DGKACES1CES2ALDH1A1LMNA | |
| SCHEMBL12504184 | 0.83 | DGKA (0.38) | DGKACES1CES2ALDH1A1LMNA | |
| SCHEMBL28425590 | 0.82 | DGKA (0.41) | DGKACES1CES2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2658877-B1 | STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY | BRIDGESTONE CORP (JP) | 2023-04-12 | — | — | EP | disclosed |
| US-9546237-B2 | Stabilization of polymers that contain a hydrolyzable functionality | BRIDGESTONE CORPORATION (JP) | 2017-01-17 | — | — | US | disclosed |
| US-9499683-B2 | Stabilization of polymers that contain a hydrolyzable functionality | BRIDGESTONE CORPORATION (JP) | 2016-11-22 | — | — | US | disclosed |
| US-20140031471-A1 | Stabilization Of Polymers That Contain A Hydrolyzable Functionality | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |
| US-20130331520-A1 | STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY | BRIDGESTONE CORPORATION (JP) | 2013-12-12 | — | — | US | disclosed |
| EP-2658877-A1 | STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY | Bridgestone Corporation (JP) | 2013-11-06 | — | — | EP | disclosed |
| WO-2012092626-A1 | STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY | BRIDGESTONE CORPORATION (JP) | 2012-07-05 | — | — | WO | disclosed |