SCHEMBL12504372

SCHEMBL12504372

CCCCCCC[Si](Cl)(CC)CC

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
THRB P10828 1/20 0.44
ALDH1A1 P00352 3/20 0.41
DNM1 Q05193 7/20 0.35
LMNA P02545 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 1/20 0.35
SLC22A1 O15245 1/20 0.35
EPHX1 P07099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8527206 1.00 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL28309952 1.00 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL8926895 1.00 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL7691169 1.00 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL12504455 1.00 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL9746242 0.97 TSHR (0.39) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL12504083 0.94 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL12504326 0.94 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL12504584 0.94 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL27956383 0.92 TSHR (0.42) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658877-B1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORP (JP) 2023-04-12 EP disclosed
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
US-9499683-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2016-11-22 US disclosed
US-20140031471-A1 Stabilization Of Polymers That Contain A Hydrolyzable Functionality BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
EP-2658877-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY Bridgestone Corporation (JP) 2013-11-06 EP disclosed
WO-2012092626-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2012-07-05 WO disclosed
US-7344235-B2 Ink composition for ink jet recording, ink cartridge, nozzle plate for ink jet recording, ink jet head, and recording apparatus MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2008-03-18 US disclosed