SCHEMBL9746242

SCHEMBL9746242

CCCCC[Si](Cl)(CC)CC

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.39
THRB P10828 1/20 0.39
ALDH1A1 P00352 3/20 0.36
LMNA P02545 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC22A1 O15245 3/20 0.32
SLC22A2 O15244 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DNM1 Q05193 5/20 0.30
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8926895 0.97 TSHR (0.44) TSHRTHRBALDH1A1LMNASLC22A1
SCHEMBL28309952 0.97 TSHR (0.44) TSHRTHRBALDH1A1LMNASLC22A1
SCHEMBL12504455 0.97 TSHR (0.44) TSHRTHRBALDH1A1LMNASLC22A1
SCHEMBL7691169 0.97 TSHR (0.44) TSHRTHRBALDH1A1LMNASLC22A1
SCHEMBL12504372 0.97 TSHR (0.44) TSHRTHRBALDH1A1LMNASLC22A1
SCHEMBL8527206 0.97 TSHR (0.44) TSHRTHRBALDH1A1LMNASLC22A1
SCHEMBL12504584 0.92 TSHR (0.44) TSHRTHRBALDH1A1LMNASLC22A1
SCHEMBL12504083 0.92 TSHR (0.44) TSHRTHRBALDH1A1LMNASLC22A1
SCHEMBL12504326 0.92 TSHR (0.44) TSHRTHRBALDH1A1LMNASLC22A1
SCHEMBL3481875 0.91 TSHR (0.35) TSHRTHRBALDH1A1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7344235-B2 Ink composition for ink jet recording, ink cartridge, nozzle plate for ink jet recording, ink jet head, and recording apparatus MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2008-03-18 US disclosed
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed