Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.54 |
| ▸ | EPOR | P19235 | 3/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6372179 | 0.88 | FOLH1 (0.55) | FOLH1EPORITGB3ITGA2BABCB1 | |
| SCHEMBL25186538 | 0.88 | FOLH1 (0.55) | FOLH1ITGB3ITGA2BABCB1CTSL | |
| SCHEMBL6372172 | 0.88 | FOLH1 (0.55) | FOLH1EPORITGB3ITGA2BABCB1 | |
| SCHEMBL25177906 | 0.87 | FOLH1 (0.54) | FOLH1ITGB3ITGA2BABCB1CTSL | |
| SCHEMBL3776750 | 0.87 | EPOR (0.51) | FOLH1EPORITGB3ITGA2BCPB1 | |
| SCHEMBL22804052 | 0.87 | EPOR (0.51) | FOLH1EPORITGB3ITGA2BCPB1 | |
| SCHEMBL1491987 | 0.87 | EPOR (0.51) | FOLH1EPORITGB3ITGA2BCPB1 | |
| SCHEMBL16446175 | 0.87 | FOLH1 (0.53) | FOLH1ITGB3ITGA2BABCB1CTSL | |
| SCHEMBL8213617 | 0.86 | EPOR (0.50) | FOLH1EPORITGB3ITGA2BCPB1 | |
| SCHEMBL8213619 | 0.86 | EPOR (0.50) | FOLH1EPORITGB3ITGA2BCPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012092629-A2 | METHODS, CELLS, AND SYSTEMS FOR INCORPORATING NON-CANONICAL AMINO ACIDS INTO PROTEINS | WATERSTONE PHARMACEUTICALS (CN) | 2012-07-05 | — | — | WO | claimed |