Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 3/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8213619 | 1.00 | EPOR (0.50) | EPORFOLH1LTA4HITGB3ITGA2B | |
| SCHEMBL22804052 | 0.88 | EPOR (0.51) | EPORFOLH1LTA4HITGB3ITGA2B | |
| SCHEMBL3776750 | 0.88 | EPOR (0.51) | EPORFOLH1LTA4HITGB3ITGA2B | |
| SCHEMBL1491987 | 0.88 | EPOR (0.51) | EPORFOLH1LTA4HITGB3ITGA2B | |
| SCHEMBL1526185 | 0.86 | EPOR (0.49) | EPORFOLH1LTA4HITGB3ITGA2B | |
| SCHEMBL3222447 | 0.86 | EPOR (0.52) | EPORFOLH1LTA4HITGB3ITGA2B | |
| SCHEMBL12504602 | 0.86 | FOLH1 (0.54) | EPORFOLH1LTA4HITGB3ITGA2B | |
| SCHEMBL10653654 | 0.86 | EPOR (0.49) | EPORFOLH1LTA4HITGB3ITGA2B | |
| SCHEMBL27513666 | 0.85 | EPOR (0.54) | EPORFOLH1LTA4HITGB3ITGA2B | |
| SCHEMBL30417019 | 0.85 | EPOR (0.54) | EPORFOLH1LTA4HITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011730-A2 | TARGETED ADDITION OF SOLUBLE POLYMERS TO RECOMBINANT PROTEINS | Edge Biosystems, Inc. (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1998015293-A2 | TARGETED ADDITION OF SOLUBLE POLYMERS TO RECOMBINANT PROTEINS | EDGE BIOSYSTEMS, INC. (US) | 1998-04-16 | — | — | WO | disclosed |