Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1250589 | 1.00 | ATM (0.34) | ATMMMP2ANPEPACERAB9A | |
| SCHEMBL1250591 | 1.00 | ATM (0.34) | ATMMMP2ANPEPACERAB9A | |
| SCHEMBL1251163 | 0.85 | ATM (0.42) | ATMMMP2ANPEP | |
| SCHEMBL6917231 | 0.85 | ATM (0.42) | ATMMMP2ANPEP | |
| SCHEMBL21682443 | 0.85 | ATM (0.42) | ATMMMP2ANPEP | |
| SCHEMBL1251161 | 0.85 | ATM (0.42) | ATMMMP2ANPEP | |
| SCHEMBL1251167 | 0.85 | ATM (0.42) | ATMMMP2ANPEP | |
| SCHEMBL20789245 | 0.83 | HSD17B10 (0.40) | — | |
| SCHEMBL15758407 | 0.82 | VDR (0.32) | MMP2ANPEP | |
| SCHEMBL25368595 | 0.76 | ATM (0.37) | ATMMMP2ANPEPRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279737-B1 | Heterocyclic compounds that are active as beta lactamase inhibitors | NOVEXEL (FR) | 2012-10-31 | — | — | EP | disclosed |
| EP-2279737-A1 | Heterocyclic compounds that are active as beta lactamase inhibitors | NOVEXEL (FR) | 2011-02-02 | — | — | EP | disclosed |
| EP-1480644-B1 | NOVEL HETEROCYCLIC COMPOUNDS WHICH ARE ACTIVE AS INHIBITORS OF BETA+LACTAMASES | NOVEXEL (FR) | 2010-10-13 | — | — | EP | disclosed |
| EP-1307457-B1 | AZABICYCLIC COMPOUNDS, PREPARATION THEREOF AND USE AS MEDICINES, IN PARTICULAR AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA SA (FR) | 2004-04-07 | — | — | EP | disclosed |