Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 1/20 | 0.58 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.58 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | IGF2R | P11717 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17734348 | 1.00 | LGALS8 (0.58) | LGALS8LGALS3LGALS4MAPK1IGF2R | |
| SCHEMBL17734353 | 1.00 | LGALS8 (0.58) | LGALS8LGALS3LGALS4MAPK1IGF2R | |
| SCHEMBL1250707 | 1.00 | LGALS8 (0.58) | LGALS8LGALS3LGALS4MAPK1IGF2R | |
| SCHEMBL7904801 | 0.98 | LGALS8 (0.60) | LGALS8LGALS3LGALS4MAPK1IGF2R | |
| SCHEMBL21878965 | 0.98 | LGALS8 (0.60) | LGALS8LGALS3LGALS4MAPK1IGF2R | |
| SCHEMBL25480881 | 0.98 | LGALS8 (0.60) | LGALS8LGALS3LGALS4MAPK1IGF2R | |
| SCHEMBL21934523 | 0.98 | LGALS8 (0.60) | LGALS8LGALS3LGALS4MAPK1IGF2R | |
| SCHEMBL20904130 | 0.98 | LGALS8 (0.60) | LGALS8LGALS3LGALS4MAPK1IGF2R | |
| SCHEMBL22817555 | 0.98 | LGALS8 (0.60) | LGALS8LGALS3LGALS4MAPK1IGF2R | |
| SCHEMBL24014792 | 0.98 | LGALS8 (0.60) | LGALS8LGALS3LGALS4MAPK1IGF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2284257-A1 | Mycobacteria expressing a cap-specific mannosyl transferase | Vereniging voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek en Patiëntenzorg (NL) | 2011-02-16 | — | — | EP | disclosed |
| US-20090017061-A1 | Mycobacteria with Mannose Cap-Deficient Lipoarabinomannan | VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS, WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG (NL) | 2009-01-15 | — | — | US | disclosed |
| EP-1841860-A2 | MYCOBACTERIA WITH MANNOSE CAP-DEFICIENT LIPOARABINOMANNAN | Vereniging voor christelijk hoger onderwijs, wetenschappelijk onderzoek en patiëntenzorg (NL) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006078164-A2 | MYCOBACTERIA WITH MANNOSE CAP-DEFICIENT LIPOARABINOMANNAN | VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS, WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG (NL) | 2006-07-27 | — | — | WO | disclosed |