Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1155109 | 1.00 | MAPK14 (0.49) | MAPK14RETCAMK1DHDAC6TBXA2R | |
| SCHEMBL11971807 | 1.00 | MAPK14 (0.49) | MAPK14RETCAMK1DHDAC6TBXA2R | |
| SCHEMBL177081 | 1.00 | MAPK14 (0.49) | MAPK14RETCAMK1DHDAC6TBXA2R | |
| SCHEMBL1595257 | 1.00 | MAPK14 (0.49) | MAPK14RETCAMK1DHDAC6TBXA2R | |
| SCHEMBL11026742 | 1.00 | MAPK14 (0.49) | MAPK14RETCAMK1DHDAC6TBXA2R | |
| SCHEMBL14325015 | 1.00 | MAPK14 (0.49) | MAPK14RETCAMK1DHDAC6TBXA2R | |
| SCHEMBL177080 | 1.00 | MAPK14 (0.49) | MAPK14RETCAMK1DHDAC6TBXA2R | |
| SCHEMBL2811047 | 1.00 | MAPK14 (0.49) | MAPK14RETCAMK1DHDAC6TBXA2R | |
| SCHEMBL14393350 | 1.00 | MAPK14 (0.49) | MAPK14RETCAMK1DHDAC6TBXA2R | |
| SCHEMBL10209588 | 1.00 | MAPK14 (0.49) | MAPK14RETCAMK1DHDAC6TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119866217-A | Agent for restoring metal steady state containing malonic acid or derivative thereof | 牛津抗生素(制药)集团股份有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-117561241-A | Inhibitors of transglutaminase | 策迪拉有限公司 | 2024-02-13 | — | — | CN | disclosed |
| WO-2023110138-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |
| EP-4192813-A1 | INHIBITORS OF TRANSGLUTAMINASES | Zedira GmbH (DE) | 2023-06-14 | — | — | EP | disclosed |
| WO-2023275336-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-01-05 | — | — | WO | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| EP-1741697-B1 | CRYSTAL COMPRISING (2R)-2-PROPYLOCTANOIC ACID AND DIBENZYLAMINE | ONO PHARMACEUTICAL CO (JP) | 2012-12-19 | — | — | EP | disclosed |
| US-8273916-B2 | Crystal comprising (2R)-2-propyloctanoic acid and amine | ONO PHARMACEUTICAL CO., LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| EP-1966146-B1 | 4,5-DIHYDRO- (1H)-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR MODULATORS | ABBOTT HEALTHCARE PRODUCTS BV (NL) | 2011-03-02 | — | — | EP | disclosed |
| EP-1664005-B1 | THIAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | ABBOTT HEALTHCARE PRODUCTS BV (NL) | 2011-02-09 | — | — | EP | disclosed |
| CN-101107233-A | 1H-imidiazole derivatives as cannabinoid CB2 receptor modulators | SOLVAY PHARM BV (NL) | 2008-01-16 | — | — | CN | disclosed |
| EP-1874734-A1 | 1H-IMIDIAZOLE DERIVATIVES AS CANNABINOID CB2 RECEPTOR MODULATORS | Solvay Pharmaceuticals B.V. (NL) | 2008-01-09 | — | — | EP | disclosed |
| WO-2007071662-A1 | 4,5-DIHYDRO- (1H)-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR MODULATORS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2007-06-28 | — | — | WO | disclosed |
| US-20070142362-A1 | 4,5-Dihydro-(1H)-pyrazole derivatives as cannabinoid CB1 receptor modulators | SOLVAY PHARMACEUTICALS B.V. | 2007-06-21 | — | — | US | disclosed |
| EP-1741697-A1 | CRYSTAL COMPRISING (2R)-2-PROPYLOCTOIC ACID AND AMINE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | disclosed |
| US-20060194779-A1 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2006-08-31 | — | — | US | disclosed |
| WO-2006087355-A1 | 1H-IMIDIAZOLE DERIVATIVES AS CANNABINOID CB2 RECEPTOR MODULATORS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2006-08-24 | — | — | WO | disclosed |
| EP-1664005-A1 | THIAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | Solvay Pharmaceuticals B.V. (NL) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005028456-A1 | THIAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2005-03-31 | — | — | WO | disclosed |
| US-20050065189-A1 | Thiazole derivatives as cannabinoid receptor modulators | SOLVAY PHARMACEUTICALS B.V. | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142362-A1 | 4,5-Dihydro-(1H)-pyrazole derivatives as cannabinoid CB1 receptor modulators | CNR1, CNR2, GPR55 | MAPK14 1260/4885RET 731/4885CAMK1D 781/4885 |
| US-20050065189-A1 | Thiazole derivatives as cannabinoid receptor modulators | CNR1, CNR2, NPY1R | MAPK14 3723/4885RET 157/4885CAMK1D 939/4885 |
| US-20060194779-A1 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | CNR1, CNR2, HRH4 | MAPK14 2132/4885RET 353/4885CAMK1D 575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.