Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12509332 | 0.89 | APP (0.59) | APPMAPTNPC1RAB9AMGAM | |
| SCHEMBL12422193 | 0.87 | MAPT (0.67) | APPMAPTTP53NPC1RAB9A | |
| SCHEMBL12509470 | 0.85 | APP (0.64) | APPMAPTTP53NPC1RAB9A | |
| SCHEMBL12509013 | 0.84 | SCD (0.57) | APPMAPTTP53NPC1RAB9A | |
| SCHEMBL1985009 | 0.82 | SCD (0.67) | APPMAPTTP53NPC1RAB9A | |
| SCHEMBL16623336 | 0.81 | MAPT (0.64) | APPMAPTTP53NPC1RAB9A | |
| SCHEMBL12509611 | 0.81 | NPC1 (0.58) | APPMAPTNPC1RAB9AMGAM | |
| SCHEMBL10311784 | 0.81 | APP (0.69) | APPNPC1RAB9ASMN1; SMN2GLA | |
| SCHEMBL1069914 | 0.80 | MAPT (0.72) | APPMAPTTP53NPC1RAB9A | |
| SCHEMBL1993188 | 0.80 | APP (0.58) | APPMAPTTP53GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | MAPT, PRNP, MAP4 | APP 17/4885MAPT 1/4885TP53 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.