Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 4/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12509332 | 0.89 | APP (0.59) | SCDAPPMAPTRAB9ANPC1 | |
| SCHEMBL12509486 | 0.87 | MAPT (0.61) | APPMAPTRAB9ANPC1TP53 | |
| SCHEMBL1983311 | 0.87 | MMP2 (0.69) | SCDAPPMAPTRAB9ANPC1 | |
| SCHEMBL2193825 | 0.87 | APP (0.60) | SCDAPPMAPTRAB9ANPC1 | |
| SCHEMBL13391954 | 0.86 | MAPT (0.58) | SCDAPPMAPTRAB9ANPC1 | |
| SCHEMBL12509611 | 0.86 | NPC1 (0.58) | SCDAPPMAPTRAB9ANPC1 | |
| SCHEMBL2195119 | 0.85 | MAPT (0.75) | SCDAPPMAPTRAB9ANPC1 | |
| SCHEMBL16256418 | 0.85 | MAPT (0.57) | SCDAPPMAPTRAB9ANPC1 | |
| SCHEMBL1985009 | 0.85 | SCD (0.67) | SCDAPPMAPTRAB9ANPC1 | |
| SCHEMBL12509529 | 0.84 | APP (0.55) | APPMAPTRAB9ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. | 2011-07-14 | — | — | US | disclosed |
| WO-2010034982-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. (SG) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | MAPT, PRNP, MAP4 | SCD 4644/4885APP 17/4885MAPT 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.