Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3676299 | 0.89 | MAPT (0.40) | ALDH1A1ALDH2MAPTCA12CA1 | |
| SCHEMBL2167597 | 0.84 | EHMT2 (0.38) | ALDH1A1ALDH2MAPTCA12CA1 | |
| SCHEMBL1250793 | 0.77 | MAPT (0.41) | ALDH1A1ALDH2MAPTCA12CA1 | |
| SCHEMBL10662731 | 0.73 | CA12 (0.46) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL9683654 | 0.69 | ALDH1A1 (0.50) | ALDH1A1ALDH2MAPTCA12CA1 | |
| SCHEMBL10664067 | 0.69 | CA12 (0.46) | ALDH1A1ALDH2CA12CA1CA2 | |
| SCHEMBL16752024 | 0.67 | TSHR (0.33) | — | |
| SCHEMBL871699 | 0.67 | — | — | |
| SCHEMBL8637059 | 0.67 | — | — | |
| SCHEMBL17151270 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434755-B1 | A NITROGEN-CONTAINING ORTHO ESTER-BASED SURFACTANT, ITS PREPARATION AND USE | AKZO NOBEL NV (NL) | 2011-02-09 | — | — | EP | disclosed |
| US-7713916-B2 | Orthoester-based surfactants and associated methods | HALLIBURTON ENERGY SERVICES, INC. (US) | 2010-05-11 | — | — | US | disclosed |
| US-7700525-B2 | Orthoester-based surfactants and associated methods | HALLIBURTON ENERGY SERVICES, INC. (US) | 2010-04-20 | — | — | US | disclosed |
| US-20100016184-A1 | Orthoester-Based Surfactants and Associated Methods | HALLIBURTON ENERGY SERVICES, INC. | 2010-01-21 | — | — | US | disclosed |
| US-7288510-B2 | Nitrogen-containing ortho ester-based surfactant, its preparation and use | AKZO NOBEL N.V. (NL) | 2007-10-30 | — | — | US | disclosed |
| US-20070066492-A1 | Orthoester-based surfactants and associated methods | HALLIBURTON ENERGY SERVICES, INC. | 2007-03-22 | — | — | US | disclosed |
| US-20070066493-A1 | Orthoester-based surfactants and associated methods | HALLIBURTON ENERGY SERVICES, INC. | 2007-03-22 | — | — | US | disclosed |
| US-20040198631-A1 | Nitrogen-containing ortho ester-based surfactant, its preparation and use | AKZO NOBEL N.V. (NL) | 2004-10-07 | — | — | US | disclosed |