Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979744 | 0.87 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10PKMKDM4E | |
| SCHEMBL9068700 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10PKMKDM4E | |
| SCHEMBL29083077 | 0.81 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10PKMKDM4E | |
| SCHEMBL11204020 | 0.81 | CYP4F2 (0.42) | ALDH1A1LMNAHSD17B10PKMKDM4E | |
| SCHEMBL3372776 | 0.81 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10PKMKDM4E | |
| Water SCHEMBL4000009 | 0.81 | MEN1 (0.44) | ALDH1A1LMNAHSD17B10PKMKDM4E | |
| SCHEMBL13807718 | 0.79 | SOAT1 (0.42) | ALDH1A1LMNAHSD17B10PKMKDM4E | |
| SCHEMBL10825861 | 0.79 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10PKMKDM4E | |
| Fluoride SCHEMBL11204021 | 0.79 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10PKMKDM4E | |
| SCHEMBL8160331 | 0.79 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930595-A | Synthetic process of isoxazoline derivative | 江苏剑牌农化股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119101010-B | Difluoromethyl thiazole amide-containing compound and application thereof as bactericide | 安徽理工大学 | 2025-04-04 | — | — | CN | claimed |
| CN-119591545-A | Synthesis method of difluoro pyrazole acid and ester and intermediate thereof | 湖北晟康化工有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-118420467-B | Method for separating methyl acetate/ethyl acetate-methanol/ethanol-water mixed solution by using NMP waste liquid | 湖南工程学院 | 2024-08-30 | — | — | CN | claimed |
| CN-118420467-A | Method for separating methyl acetate/ethyl acetate-methanol/ethanol-water mixed solution by using NMP waste liquid | 湖南工程学院 | 2024-08-02 | — | — | CN | claimed |
| CN-114957123-B | 3- (difluoromethyl) -pyrazole-4-carboxylic ester derivative and preparation method and application thereof | 浙江工业大学 | 2023-11-28 | — | — | CN | claimed |
| CN-114210288-B | 1, 1-difluoroacetone production device and production method thereof | 科莱博(江苏)科技股份有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-218248556-U | Difluoro acetoacetic ester apparatus for producing | 福建久策气体股份有限公司 | 2023-01-10 | — | — | CN | claimed |
| CN-112574039-B | Synthesis method of ethyl difluoroacetoacetate | 湖南海利化工股份有限公司 | 2022-12-16 | — | — | CN | claimed |
| CN-115282894-A | Difluoro ethyl acetoacetate production device and working method thereof | 福建久策气体股份有限公司 | 2022-11-04 | — | — | CN | claimed |
| CN-112574039-A | Synthesis method of ethyl difluoroacetoacetate | 湖南海利化工股份有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-110669007-A | 3- (difluoromethyl) -1-methyl-1H-pyrazole-4-carboxylic ester compound and preparation method and application thereof | 浙江工业大学 | 2020-01-10 | — | — | CN | claimed |
| CN-110615764-A | N- (2-benzamide) -1H-pyrazole-4-formamide compound and preparation method and application thereof | 浙江工业大学 | 2019-12-27 | — | — | CN | claimed |
| EP-2571854-B1 | METHOD FOR MANUFACTURING 1-ALKYL-3-DIFLUORMETHYL-5-HYDROXYPYRAZOLES | BAYER IP GMBH (DE) | 2014-11-05 | — | — | EP | claimed |
| US-8455664-B2 | Process for preparing 1-alkyl-3-difluoromethyl-5-hydroxypyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-06-04 | — | — | US | claimed |
| EP-2571854-A1 | METHOD FOR MANUFACTURING 1 - ALKYL - 3 - DIFLUORMETHYL - 5 - HYDROXYPYRAZOLES | Bayer Intellectual Property GmbH (DE) | 2013-03-27 | — | — | EP | claimed |
| WO-2011144549-A1 | METHOD FOR MANUFACTURING 1 - ALKYL - 3 - DIFLUORMETHYL - 5 - HYDROXYPYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2011-11-24 | — | — | WO | claimed |
| US-20110288304-A1 | Process for Preparing 1-Alkyl-3-difluoromethyl-5-hydroxypyrazoles | BAYER CROPSCIENCE AG (DE) | 2011-11-24 | — | — | US | claimed |
| EP-0135491-B1 | HERBICIDAL 2,6-BIS-FLUOROMETHYL-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTERS | MONSANTO COMPANY (US) | 1989-01-25 | — | — | EP | claimed |
| EP-0135491-A1 | Herbicidal 2,6-bis-fluoromethyl-dihydropyridine-3,5-dicarboxylic acid esters | MONSANTO COMPANY (US) | 1985-03-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288304-A1 | Process for Preparing 1-Alkyl-3-difluoromethyl-5-hydroxypyrazoles | CYP51A1, CYP3A5, CYP4F3 | ALDH1A1 272/4885LMNA 3430/4885HSD17B10 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.