Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10198852 | 0.95 | MTNR1A (0.46) | MTNR1AMTNR1BCYP1A2HTTSMN1; SMN2 | |
| SCHEMBL12444102 | 0.91 | MTNR1A (0.43) | MTNR1AMTNR1BCYP1A2HTTSMN1; SMN2 | |
| SCHEMBL19445539 | 0.88 | MTNR1A (0.41) | MTNR1AMTNR1BCYP1A2HTTSMN1; SMN2 | |
| SCHEMBL12515350 | 0.87 | MAPK14 (0.41) | MTNR1AMTNR1BCYP1A2HTTSMN1; SMN2 | |
| SCHEMBL10268065 | 0.87 | MAPK14 (0.41) | MTNR1AMTNR1BCYP1A2HTTSMN1; SMN2 | |
| SCHEMBL19445567 | 0.86 | MTNR1A (0.41) | MTNR1AMTNR1BCYP1A2HTTSMN1; SMN2 | |
| SCHEMBL13351617 | 0.86 | HTT (0.40) | MTNR1AMTNR1BCYP1A2HTTSMN1; SMN2 | |
| SCHEMBL16284392 | 0.85 | MTNR1A (0.39) | MTNR1AMTNR1BCYP1A2HTTSMN1; SMN2 | |
| SCHEMBL21864682 | 0.85 | MTNR1A (0.39) | MTNR1AMTNR1BCYP1A2HTTSMN1; SMN2 | |
| SCHEMBL11947670 | 0.85 | MTNR1A (0.39) | MTNR1AMTNR1BCYP1A2HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084970-A1 | ANTI-HEPARIN COMPOUNDS | POLYMEDIX INC. (US) | 2011-07-14 | — | — | WO | disclosed |