SCHEMBL12518540

SCHEMBL12518540

CCC(=O)NCCCCC(NC(=O)COCCOCCNC(=O)CCC(C)C(=O)O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.60
▸ NOD1 Q9Y239 4/20 0.40
▸ C3AR1 Q16581 1/20 0.39
▸ FOLH1 Q04609 3/20 0.39
▸ ALB P02768 2/20 0.38
▸ EPHX2 P34913 1/20 0.36
▸ CCKAR P32238 1/20 0.36
▸ CCKBR P32239 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424086 0.99 GLP1R (0.62) GLP1RNOD1C3AR1FOLH1ALB
SCHEMBL22627100 0.92 GLP1R (0.58) GLP1RC3AR1FOLH1ALB
SCHEMBL16478790 0.91 GLP1R (0.57) GLP1RNOD1C3AR1FOLH1ALB
SCHEMBL19261649 0.90 GLP1R (0.58) GLP1RNOD1C3AR1FOLH1ALB
SCHEMBL17401159 0.88 GLP1R (0.64) GLP1RNOD1C3AR1FOLH1CCKAR
SCHEMBL21172198 0.88 GLP1R (0.61) GLP1RNOD1C3AR1FOLH1
SCHEMBL21172401 0.88 GLP1R (0.47) GLP1RFOLH1
SCHEMBL21172251 0.87 GLP1R (0.62) GLP1RNOD1C3AR1FOLH1EPHX2
SCHEMBL19069582 0.87 GLP1R (0.56) GLP1RC3AR1FOLH1ALB
SCHEMBL21172359 0.87 GLP1R (0.49) GLP1RFOLH1CCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2981282-B1 GROWTH HORMONE COMPOUND FORMULATION NOVO NORDISK HEALTHCARE AG (CH) 2020-11-04 — — EP disclosed
EP-2525834-B1 GROWTH HORMONES WITH PROLONGED IN-VIVO EFFICACY NOVO NORDISK HEALTHCARE AG (CH) 2019-07-17 — — EP disclosed
WO-2011089255-A1 GROWTH HORMONES WITH PROLONGED IN-VIVO EFFICACY NOVO NORDISK HEALTH CARE AG (CH) 2011-07-28 — — WO disclosed
Send feedback