SCHEMBL16478790

SCHEMBL16478790

CC(CCC(=O)NCCOCCOCC(=O)N[C@@H](CCCCNC(=O)CBr)C(=O)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.57
▸ C3AR1 Q16581 1/20 0.39
▸ FOLH1 Q04609 4/20 0.38
▸ NOD1 Q9Y239 3/20 0.38
▸ ALB P02768 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19261649 0.99 GLP1R (0.58) GLP1RC3AR1FOLH1NOD1ALB
SCHEMBL12518540 0.91 GLP1R (0.60) GLP1RC3AR1FOLH1NOD1ALB
SCHEMBL22627100 0.91 GLP1R (0.58) GLP1RC3AR1FOLH1ALB
SCHEMBL12424086 0.90 GLP1R (0.62) GLP1RC3AR1FOLH1NOD1ALB
SCHEMBL19155407 0.90 GLP1R (0.62) GLP1RC3AR1FOLH1NOD1ALB
SCHEMBL15850016 0.90 GLP1R (0.59) GLP1RC3AR1FOLH1ALB
SCHEMBL19261650 0.89 GLP1R (0.50) GLP1R
SCHEMBL15850015 0.89 GLP1R (0.66) GLP1RFOLH1NOD1
SCHEMBL15871502 0.89 GLP1R (0.61) GLP1RC3AR1FOLH1NOD1ALB
SCHEMBL19286716 0.87 GLP1R (0.53) GLP1RC3AR1FOLH1ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9737612-B2 Antagonistic DR3 ligands NOVO NORDISK A/S (DK) 2017-08-22 — — US disclosed
US-20140107324-A1 Growth Hormones with Prolonged In-Vivo Efficacy NOVO NORDISK HEALTH CARE AG (CH) 2014-04-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140107324-A1 Growth Hormones with Prolonged In-Vivo Efficacy SHBG, GHRHR, GHITM GLP1R 101/4885C3AR1 1771/4885FOLH1 469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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