⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744163 | 0.77 | — | — | |
| SCHEMBL22967340 | 0.72 | — | — | |
| SCHEMBL27643559 | 0.71 | ALDH1A1 (0.38) | — | |
| SCHEMBL464885 | 0.69 | — | — | |
| SCHEMBL24908259 | 0.69 | TSHR (0.35) | — | |
| Formaldehyde SCHEMBL29225333 | 0.67 | — | — | |
| Ethylene SCHEMBL27770741 | 0.67 | — | — | |
| SCHEMBL27797811 | 0.67 | — | — | |
| SCHEMBL10974000 | 0.65 | — | — | |
| SCHEMBL11354902 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012125900-A1 | 2'-ALLENE-SUBSTITUTED NUCLEOSIDE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2012-09-20 | — | — | WO | disclosed |
| EP-2266965-A1 | Methods for Isolating Crystalline Form I of 5-Azacytidine | Celgene International Sarl (CH) | 2010-12-29 | — | — | EP | disclosed |
| EP-2181988-A1 | Pharmaceutical Compositions based on Crystalline Form I of 5-Azacytidine | Pharmion Corporation (US) | 2010-05-05 | — | — | EP | disclosed |
| WO-2010014883-A2 | AZACITIDINE PROCESS AND POLYMORPHS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-02-04 | — | — | WO | disclosed |
| WO-2009042767-A1 | AZACYTIDINE ANALOGUES AND USES THEREOF | MOUNT SINAI SCHOOL OF MEDICINE (US) | 2009-04-02 | — | — | WO | disclosed |
| WO-2009016617-A2 | STABLE HIGHLY PURE AZACITIDINE AND PREPARATION METHODS THEREFOR | CHEMAGIS LTD. (IL) | 2009-02-05 | — | — | WO | disclosed |