Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12166205 | 0.79 | GPR119 (0.43) | L3MBTL1MAPTGPR119 | |
| SCHEMBL12166199 | 0.76 | HRH3 (0.46) | L3MBTL1MAPTHRH3 | |
| SCHEMBL12166211 | 0.75 | HRH3 (0.50) | HRH3 | |
| SCHEMBL12166210 | 0.73 | GPR119 (0.34) | MAPTHRH3GPR119 | |
| SCHEMBL12166202 | 0.68 | TYK2 (0.33) | HRH3 | |
| SCHEMBL12166223 | 0.66 | HRH3 (0.33) | HRH3 | |
| SCHEMBL15362506 | 0.65 | HRH3 (0.47) | HRH3 | |
| SCHEMBL12166208 | 0.65 | CHRNA7 (0.34) | GPR119 | |
| SCHEMBL12166200 | 0.64 | GPR119 (0.31) | MAPTGPR119 | |
| SCHEMBL15362463 | 0.64 | GPR119 (0.41) | L3MBTL1MAPTHRH3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012122077-A1 | PRIMARY AMINE DIAZENIUMDIOLATE HETEROCYCLIC DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-09-13 | — | — | WO | disclosed |