Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 3/20 | 0.66 |
| ▸ | KMO | O15229 | 2/20 | 0.61 |
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | F11 | P03951 | 1/20 | 0.56 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.56 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | FNTA | P49354 | 2/20 | 0.55 |
| ▸ | FNTB | P49356 | 2/20 | 0.55 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | BCL2 | P10415 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1855849 | 0.89 | KMO (0.67) | CFDKMOFNTAFNTBPGGT1B | |
| SCHEMBL31500915 | 0.89 | FOLH1 (0.66) | NR4A2FOLH1LOXL2 | |
| SCHEMBL31500919 | 0.89 | FOLH1 (0.66) | NR4A2FOLH1LOXL2 | |
| SCHEMBL61226 | 0.89 | FOLH1 (0.66) | NR4A2FOLH1LOXL2 | |
| Hydrochloric Acid SCHEMBL1853944 | 0.88 | KMO (0.65) | CFDKMOFNTAFNTBPGGT1B | |
| SCHEMBL14496864 | 0.88 | BCL2 (0.71) | CFDRXRARXRBBCL2LOXL2 | |
| Hydrochloric Acid SCHEMBL4232340 | 0.87 | FOLH1 (0.63) | FOLH1LOXL2 | |
| Water SCHEMBL8887800 | 0.87 | FOLH1 (0.63) | FOLH1LOXL2 | |
| Isophthalic Acid SCHEMBL9858510 | 0.87 | FOLH1 (0.58) | CFDPLAUNR4A2FOLH1LOXL2 | |
| Hydrochloric Acid SCHEMBL6720898 | 0.86 | KMO (0.62) | CFDKMOFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611692-B2 | bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2009-11-03 | — | — | US | claimed |
| US-6011175-A | Inhibition of farnesyltransferase | UNIVERSITY OF PITTSBURGH (US) | 2000-01-04 | — | — | US | claimed |
| EP-2500040-A1 | Improved Gastrin Releasing Peptide Receptor-Binding Compounds | Bracco Imaging S.p.A (IT) | 2012-09-19 | — | — | EP | disclosed |
| EP-2281580-A2 | Labeled gastrin releasing peptides (GRP) | Bracco Imaging S.p.A (IT) | 2011-02-09 | — | — | EP | disclosed |
| CN-1080257-C | Guanidine derivatives as inhibitors of Na+/H+ exchange in cells | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-03-06 | — | — | CN | disclosed |
| US-5965539-A | PEPTIDOMIMETICS; ANTI-CANCER DRUGS | UNIVERISTY OF PITTSBURGH (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0794789-A4 | INHIBITORS OF PRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 1999-05-26 | — | — | EP | disclosed |
| US-5856310-A | ANTITUMOR AGENTS | UNIVERSITY OF PITTSBURGH (US) | 1999-01-05 | — | — | US | disclosed |
| US-5834434-A | PEPTIDOMIMETICS | UNIVERSITY OF PITTSBURGH (US) | 1998-11-10 | — | — | US | disclosed |
| EP-0794789-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1997-09-17 | — | — | EP | disclosed |
| US-5602098-A | ANTICANCER AGENT | UNIVERSITY OF PITTSBURGH (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996021456-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1996-07-18 | — | — | WO | disclosed |
| CN-1123545-A | Guanidine derivatives as inhibitors of Na+/H+ exchange in cells | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-05-29 | — | — | CN | disclosed |