SCHEMBL12525396

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12525403	0.87	SCN9A (0.42)	AOC3NR4A2F2RL3PDCD1CD274
	SCHEMBL12525397	0.85	AOC3 (0.39)	AOC3NR4A2PDCD1CD274LRRK2
	SCHEMBL18430335	0.82	AOC3 (0.38)	AOC3NR4A2PDCD1CD274LRRK2
	SCHEMBL12526321	0.79	NR4A2 (0.48)	AOC3NR4A2PDCD1CD274LRRK2
	SCHEMBL12526579	0.78	KCNH2 (0.42)	AOC3NR4A2PDCD1CD274LRRK2
	SCHEMBL15000918	0.78	FFAR1 (0.41)	AOC3KDM4EALDH1A1
	SCHEMBL12525420	0.78	AOC3 (0.52)	AOC3GRIN2BKDM4EALDH1A1
	SCHEMBL15000979	0.77	AOC3 (0.47)	AOC3NR4A2LRRK2
	SCHEMBL12526333	0.76	AOC3 (0.49)	AOC3
	SCHEMBL12525399	0.76	CYP11B1 (0.45)	AOC3PDCD1CD274GRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.