SCHEMBL12525397

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12525403	0.86	SCN9A (0.42)	AOC3NR4A2LRRK2PDCD1CD274
	SCHEMBL12525396	0.85	AOC3 (0.40)	AOC3NR4A2LRRK2PDCD1CD274
	SCHEMBL15000918	0.82	FFAR1 (0.41)	AOC3
	SCHEMBL15000542	0.81	NR4A2 (0.35)	AOC3NR4A2LRRK2PDCD1CD274
	SCHEMBL12526543	0.80	DGAT1 (0.41)	AOC3NR4A2LRRK2PDCD1CD274
	SCHEMBL15000915	0.80	AOC3 (0.41)	AOC3NR4A2LRRK2KRASADRB2
	SCHEMBL18430335	0.79	AOC3 (0.38)	AOC3NR4A2LRRK2PDCD1CD274
	SCHEMBL12525399	0.78	CYP11B1 (0.45)	AOC3PDCD1CD274KRAS
	SCHEMBL12526552	0.78	MYC (0.35)	AOC3NR4A2LRRK2HIF1A
	SCHEMBL12525395	0.78	AOC3 (0.37)	AOC3NR4A2LRRK2SCN9AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.