Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.52 |
| ▸ | MME | P08473 | 6/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12527927 | 0.93 | ACE (0.46) | ACEMME | |
| SCHEMBL12527637 | 0.91 | ACE (0.49) | ACEMME | |
| SCHEMBL12526745 | 0.87 | MME (0.48) | ACEMME | |
| SCHEMBL12495059 | 0.87 | MME (0.48) | ACEMME | |
| SCHEMBL12528549 | 0.85 | ACE (0.49) | ACEMME | |
| SCHEMBL12526742 | 0.85 | MME (0.46) | ACEMME | |
| SCHEMBL12526768 | 0.83 | ACE (0.42) | ACEMME | |
| SCHEMBL12528426 | 0.82 | ACE (0.54) | ACEMME | |
| SCHEMBL12527695 | 0.80 | ACE (0.43) | ACEMME | |
| SCHEMBL17771376 | 0.80 | ACE (0.43) | ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346852-B2 | Substituted adipic acid amides and uses thereof | BRISTOL-MYERS SCUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |
| US-9346852-B2 | Substituted adipic acid amides and uses thereof | BRISTOL-MYERS SCUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |
| WO-2012125622-A1 | SUBSTITUTED ADIPIC ACID AMIDES AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-09-20 | — | — | WO | disclosed |