Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 9/20 | 0.72 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.72 |
| ▸ | DDX3X | O00571 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17318698 | 0.88 | NPC1 (0.64) | DDX3XNPC1RAB9AMEN1KMT2A | |
| SCHEMBL17318586 | 0.85 | KDM4E (0.66) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL17318553 | 0.84 | NPC1 (0.61) | DDX3XNPC1RAB9AMEN1KMT2A | |
| SCHEMBL12700360 | 0.80 | DDX3X (0.84) | CSNK2A2CSNK2A1DDX3XNPC1RAB9A | |
| SCHEMBL11386627 | 0.78 | KMT2A (0.67) | CSNK2A2CSNK2A1NPC1RAB9AMEN1 | |
| SCHEMBL15507356 | 0.76 | CSNK2A2 (0.74) | CSNK2A2CSNK2A1NPC1RAB9A | |
| SCHEMBL13357697 | 0.75 | DDX3X (0.76) | CSNK2A2CSNK2A1DDX3XNPC1RAB9A | |
| SCHEMBL5238426 | 0.75 | HPGD (0.77) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11480689 | 0.75 | CSNK2A2 (0.83) | CSNK2A2CSNK2A1NPC1RAB9AMEN1 | |
| SCHEMBL15507119 | 0.75 | CSNK2A2 (0.72) | CSNK2A2CSNK2A1DDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012121168-A1 | KINASE INHIBITOR | 国立大学法人京都大学 (JP) | 2012-09-13 | — | — | WO | disclosed |