Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | REN | P00797 | 11/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16471529 | 0.94 | PDE4B (0.43) | PDE4BRENPDE4APDE4CPDE4D | |
| SCHEMBL16471531 | 0.84 | REN (0.51) | PDE4BREN | |
| SCHEMBL16471534 | 0.80 | REN (0.65) | REN | |
| SCHEMBL17779669 | 0.80 | REN (0.55) | REN | |
| SCHEMBL16471538 | 0.79 | REN (0.51) | PDE4BREN | |
| SCHEMBL12525835 | 0.78 | REN (0.56) | REN | |
| SCHEMBL28041417 | 0.78 | REN (0.56) | REN | |
| SCHEMBL12525491 | 0.78 | REN (0.56) | REN | |
| SCHEMBL12526539 | 0.78 | REN (0.56) | REN | |
| SCHEMBL16471580 | 0.78 | REN (0.64) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012124775-A1 | NITROGEN-CONTAINING SATURATED HETEROCYCLIC COMPOUND | 田辺三菱製薬株式会社 (JP) | 2012-09-20 | — | — | WO | disclosed |