Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.56 |
| ▸ | CALML3 | P27482 | 7/20 | 0.48 |
| ▸ | MAOB | P27338 | 9/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SDHA | P31040 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12527576 | 1.00 | MAOA (0.56) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL12527579 | 0.92 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL12527569 | 0.92 | MAOA (0.55) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL12527598 | 0.90 | MAOA (0.53) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL12525587 | 0.90 | MAOA (0.53) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL12528409 | 0.90 | MAOA (0.73) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL12527581 | 0.89 | MAOA (0.52) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL12528481 | 0.89 | MAOA (0.52) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL12527571 | 0.87 | MAOA (0.53) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL13428676 | 0.86 | MAOA (0.61) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012121424-A1 | NOVEL OXAZOLIDINONE DERIVATIVE HAVING CYCLIC AMIDRAZONE GROUP AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | (주)레고켐바이오사이언스 (KR) | 2012-09-13 | — | — | WO | disclosed |