Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 18/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1913414 | 0.83 | PDPK1 (0.61) | PDPK1 | |
| SCHEMBL1913448 | 0.79 | PDPK1 (0.50) | PDPK1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL1913547 | 0.79 | PDPK1 (0.50) | PDPK1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL1913619 | 0.79 | PDPK1 (0.50) | PDPK1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL1913537 | 0.73 | PDPK1 (0.59) | PDPK1 | |
| SCHEMBL12530706 | 0.72 | PDPK1 (0.40) | PDPK1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL1913606 | 0.72 | PDPK1 (0.49) | PDPK1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL1913605 | 0.72 | PDPK1 (0.49) | PDPK1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL1913434 | 0.69 | PDPK1 (0.66) | PDPK1 | |
| SCHEMBL16639058 | 0.68 | PDPK1 (0.49) | PDPK1CCNT1CCNA2CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076316-A1 | PYRROLOPYRIDINYL-PYRIMIDIN-2-YLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2011-06-30 | — | — | WO | disclosed |