Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 19/20 | 0.67 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1913534 | 0.90 | PDPK1 (0.64) | PDPK1ALK | |
| SCHEMBL1913597 | 0.90 | PDPK1 (0.64) | PDPK1ALK | |
| SCHEMBL1913630 | 0.90 | PDPK1 (0.64) | PDPK1ALK | |
| SCHEMBL13554583 | 0.88 | PDPK1 (0.71) | PDPK1 | |
| SCHEMBL13554584 | 0.88 | PDPK1 (0.71) | PDPK1 | |
| SCHEMBL1913401 | 0.88 | PDPK1 (0.71) | PDPK1 | |
| SCHEMBL1913432 | 0.84 | PDPK1 (0.65) | PDPK1 | |
| SCHEMBL1913407 | 0.83 | PDPK1 (0.62) | PDPK1 | |
| SCHEMBL1913527 | 0.83 | PDPK1 (0.62) | PDPK1 | |
| SCHEMBL12530656 | 0.82 | PDPK1 (0.65) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076316-A1 | PYRROLOPYRIDINYL-PYRIMIDIN-2-YLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2011-06-30 | — | — | WO | disclosed |