Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1204717 | 0.74 | HCAR2 (0.46) | HPGDTSHR | |
| SCHEMBL26448116 | 0.71 | HPGD (0.40) | HPGDTSHR | |
| SCHEMBL2827757 | 0.70 | HPGD (0.46) | HPGDTSHR | |
| SCHEMBL10697024 | 0.69 | HPGD (0.36) | HPGDTSHR | |
| SCHEMBL1055147 | 0.67 | SLC2A1 (0.35) | HPGDTSHR | |
| SCHEMBL12162717 | 0.64 | HPGD (0.38) | HPGDTSHR | |
| SCHEMBL1205789 | 0.62 | HPGD (0.46) | HPGDTSHR | |
| SCHEMBL179497 | 0.62 | HPGD (0.50) | HPGDTSHR | |
| SCHEMBL12930817 | 0.62 | HPGD (0.55) | HPGDTSHR | |
| SCHEMBL2658376 | 0.62 | PLA2G10 (0.44) | HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283001-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |