Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13184146 | 0.81 | MAPT (0.45) | HPGDTSHRMAPTHCAR2DAO | |
| SCHEMBL21233312 | 0.81 | MAPT (0.45) | HPGDTSHRMAPTHCAR2DAO | |
| SCHEMBL192831 | 0.78 | DHODH (0.44) | HPGDTSHRMAPTHCAR2DAO | |
| SCHEMBL1206509 | 0.76 | HPGD (0.56) | HPGDTSHRMAPTHCAR2DAO | |
| SCHEMBL1205789 | 0.75 | HPGD (0.46) | HPGDTSHRDAOL3MBTL1NPC1 | |
| SCHEMBL16423877 | 0.75 | HPGD (0.55) | HPGDTSHRMAPTHCAR2LMNA | |
| SCHEMBL13004470 | 0.75 | HPGD (0.55) | HPGDTSHRMAPTLMNAPDE8B | |
| SCHEMBL28214128 | 0.75 | HPGD (0.55) | HPGDTSHRMAPTLMNAPDE8B | |
| SCHEMBL12930817 | 0.75 | HPGD (0.55) | HPGDTSHRMAPTLMNAPDE8B | |
| SCHEMBL21720026 | 0.73 | HPGD (0.44) | HPGDTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110045191-A1 | MIXED-BLOCKED POLYISOCYANATES AND USES THEREOF | JONES RICHARD GARFIELD | 2011-02-24 | — | — | US | claimed |
| US-20040067318-A1 | Mixed-blocked polyisocyanates and uses thereof | BAXENDEN CHEMICALS LIMITED (GB) | 2004-04-08 | — | — | US | claimed |
| EP-1358242-A1 | MIXED-BLOCKED POLYISOCYANATES AND USES THEREOF | BAXENDEN CHEMICALS LIMITED (GB) | 2003-11-05 | — | — | EP | claimed |
| WO-2002055577-A1 | MIXED-BLOCKED POLYISOCYANATES AND USES THEREOF | BAXENDEN CHEMICALS LIMITED (GB) | 2002-07-18 | — | — | WO | claimed |
| US-20250099448-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2025-03-27 | — | — | US | disclosed |
| US-20240239809-A1 | THERAPEUTIC AGENTS FOR ENHANCING EPITHELIAL AND/OR ENDOTHELIAL BARRIER FUNCTION | ARTUS THERAPEUTICS INC (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240209000-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE LLC | 2024-06-27 | — | — | US | disclosed |
| US-20240209000-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE LLC | 2024-06-27 | — | — | US | disclosed |
| US-12019371-B2 | Photosensitive composition, film, color filter, solid-state imaging element, and image display device | FUJIFILM CORPORATION (JP) | 2024-06-25 | — | — | US | disclosed |
| US-12019371-B2 | Photosensitive composition, film, color filter, solid-state imaging element, and image display device | FUJIFILM CORPORATION (JP) | 2024-06-25 | — | — | US | disclosed |
| EP-4289427-A1 | DIHYDRO[1,8]NAPHTHYRIDIN-7-ONE AND PYRIDO[3,2-B][1,4]OXAZIN-3-ONE FOR USE IN TREATING CANCER, AND METASTASES IN PARTICULAR. | Anagenesis Biotechnologies (FR) | 2023-12-13 | — | — | EP | disclosed |
| US-20230364097-A1 | TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS | INFINITY PHARMACEUTICALS, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| EP-1358242-B1 | MIXED-BLOCKED POLYISOCYANATES AND USES THEREOF | BAXENDEN CHEM (GB) | 2006-03-15 | — | — | EP | disclosed |
| US-6881802-B2 | Catalyst for addition polymerization and process for producing an addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-19 | — | — | US | disclosed |
| US-20040067318-A1 | Mixed-blocked polyisocyanates and uses thereof | BAXENDEN CHEMICALS LIMITED (GB) | 2004-04-08 | — | — | US | disclosed |
| EP-1358242-A1 | MIXED-BLOCKED POLYISOCYANATES AND USES THEREOF | BAXENDEN CHEMICALS LIMITED (GB) | 2003-11-05 | — | — | EP | disclosed |
| US-20030032743-A1 | Catalyst for addition polymerization and process for producing an addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-02-13 | — | — | US | disclosed |
| EP-1266911-A1 | Catalyst for addition polymerization and process for producing an addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-18 | — | — | EP | disclosed |
| WO-2002055577-A1 | MIXED-BLOCKED POLYISOCYANATES AND USES THEREOF | BAXENDEN CHEMICALS LIMITED (GB) | 2002-07-18 | — | — | WO | disclosed |
| EP-0139183-A2 | Herbicidal agents containing a photosynthesis inhibitor herbicide together with substituted azolyl derivatives | BAYER AG (DE) | 1985-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240209000-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | PIK3CA, PIK3CG, PIK3CD | HPGD 2554/4885TSHR 4595/4885MAPT 1341/4885 |
| US-20030032743-A1 | Catalyst for addition polymerization and process for producing an addition polymer | BRAP, MCM4, BOLA2; BOLA2B | HPGD 3876/4885TSHR 4795/4885MAPT 749/4885 |
| US-20250099448-A1 | HETEROCYCLIC COMPOUNDS | OPRM1, CYP1A1, CYP3A4 | HPGD 352/4885TSHR 630/4885MAPT 2210/4885 |
| US-20240239809-A1 | THERAPEUTIC AGENTS FOR ENHANCING EPITHELIAL AND/OR ENDOTHELIAL BARRIER FUNCTION | LIPG, FABP2, EPCAM | HPGD 339/4885TSHR 4301/4885MAPT 3610/4885 |
| US-20230364097-A1 | TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS | PIK3CA, MCL1, PIK3CB | HPGD 2431/4885TSHR 2387/4885MAPT 4584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.