Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1250775 | 0.92 | MEN1 (0.37) | CNR2MAPTMAPK14MEN1KMT2A | |
| SCHEMBL1253174 | 0.90 | PHGDH (0.33) | KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1250781 | 0.80 | CNR2 (0.39) | CNR2MAPTMAPK13MAPK12MAPK11 | |
| SCHEMBL1250768 | 0.78 | CNR2 (0.39) | CNR2MAPTMAPK13MAPK12MAPK11 | |
| SCHEMBL351891 | 0.76 | CNR2 (0.47) | CNR2MAPTMAPK13MAPK12MAPK11 | |
| SCHEMBL1253138 | 0.76 | CNR2 (0.39) | CNR2 | |
| SCHEMBL1252448 | 0.71 | AR (0.32) | MEN1KMT2AALDH1A1 | |
| SCHEMBL1250777 | 0.70 | ALDH1A1 (0.34) | CNR2MAPK14MEN1KMT2AALDH1A1 | |
| SCHEMBL10147503 | 0.69 | MAPT (0.37) | CNR2MAPTMAPK13MAPK12MAPK11 | |
| SCHEMBL353288 | 0.69 | CNR2 (0.37) | CNR2MAPTMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283001-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2011-02-16 | — | — | EP | claimed |
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | claimed |