SCHEMBL1253142

SCHEMBL1253142

CC(CS(=O)(=O)CC1CCOCC1)c1noc(-c2cc(C(C)(C)C)nn2C)n1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.37
CNR1 P21554 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1253138 0.80 CNR2 (0.39) CNR2CNR1
SCHEMBL352079 0.79 CNR2 (0.41) CNR2CNR1
SCHEMBL1253625 0.78 CNR2 (0.35) CNR2CNR1
SCHEMBL10147585 0.71 CNR2 (0.33) CNR2CNR1
SCHEMBL1252395 0.71 CNR2 (0.41) CNR2CNR1
SCHEMBL1250804 0.70 CNR2 (0.42) CNR2CNR1
SCHEMBL1253139 0.69 CNR2 (0.37) CNR2CNR1
SCHEMBL351110 0.68 CNR2 (0.39) CNR2CNR1
SCHEMBL1252399 0.67 CNR2 (0.38) CNR2CNR1
SCHEMBL351700 0.66 CNR2 (0.36) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2283001-A2 SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR Boehringer Ingelheim International GmbH (DE) 2011-02-16 EP claimed
WO-2009140089-A2 SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-11-19 WO claimed