Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 18/20 | 0.42 |
| ▸ | CNR1 | P21554 | 6/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252395 | 0.85 | CNR2 (0.41) | CNR2CNR1 | |
| SCHEMBL1252399 | 0.82 | CNR2 (0.38) | CNR2CNR1 | |
| SCHEMBL351342 | 0.79 | CNR2 (0.46) | CNR2CNR1 | |
| SCHEMBL10147797 | 0.72 | CNR2 (0.35) | CNR2CNR1 | |
| SCHEMBL351301 | 0.71 | CNR2 (0.46) | CNR2CNR1 | |
| SCHEMBL352505 | 0.71 | CNR2 (0.43) | CNR2CNR1 | |
| SCHEMBL1253142 | 0.70 | CNR2 (0.37) | CNR2CNR1 | |
| SCHEMBL10147475 | 0.70 | ALDH1A1 (0.33) | CNR2HDAC6 | |
| SCHEMBL351388 | 0.68 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL350081 | 0.68 | CNR2 (0.42) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283001-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2011-02-16 | — | — | EP | claimed |
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | claimed |