Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198459 | 1.00 | MAPT (0.52) | MAPTNPSR1KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL9193099 | 0.82 | MAPT (0.52) | MAPTNPSR1KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL27700604 | 0.82 | KEAP1 (0.54) | MAPTNPSR1KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL27821813 | 0.82 | KEAP1 (0.54) | MAPTNPSR1KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL2062914 | 0.80 | KEAP1 (0.56) | MAPTNPSR1KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL4889259 | 0.80 | KEAP1 (0.51) | MAPTNPSR1KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL2062409 | 0.80 | KEAP1 (0.56) | MAPTNPSR1KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL28606057 | 0.79 | MAPT (0.41) | MAPTNPSR1KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL10954780 | 0.79 | CHRM3 (0.48) | MAPTNPSR1KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL4470158 | 0.78 | KEAP1 (0.44) | MAPTNPSR1KEAP1NFE2L2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2327765-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2327766-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2327767-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2319919-A1 | Nitrilases | Verenium Corporation (US) | 2011-05-11 | — | — | EP | disclosed |
| EP-2039762-A2 | Nitralases | Verenium Corporation (US) | 2009-03-25 | — | — | EP | disclosed |