Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL555454 | 1.00 | KDM4E (0.66) | KDM4EALDH1A1KMT2AMEN1GLA | |
| SCHEMBL164218 | 0.95 | KDM4E (0.59) | KDM4EALDH1A1KMT2AMEN1GLA | |
| SCHEMBL516054 | 0.95 | KDM4E (0.59) | KDM4EALDH1A1KMT2AMEN1GLA | |
| SCHEMBL6200 | 0.91 | KMT2A (0.51) | KDM4EALDH1A1KMT2AMEN1GLA | |
| SCHEMBL18770758 | 0.91 | KMT2A (0.51) | KDM4EALDH1A1KMT2AMEN1GLA | |
| Water SCHEMBL108075 | 0.89 | KMT2A (0.50) | KDM4EALDH1A1KMT2AMEN1GLA | |
| SCHEMBL5492635 | 0.89 | KMT2A (0.50) | KDM4EALDH1A1KMT2AMEN1GLA | |
| Hydrochloric Acid SCHEMBL5962066 | 0.89 | GLA (0.52) | KDM4EALDH1A1KMT2AMEN1GLA | |
| SCHEMBL29027430 | 0.89 | KMT2A (0.50) | KDM4EALDH1A1KMT2AMEN1GLA | |
| Water SCHEMBL659931 | 0.89 | KMT2A (0.50) | KDM4EALDH1A1KMT2AMEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120156709-A1 | Electrochemical Assay for the Detection of Enzymes | OHMX CORPORATION (US) | 2012-06-21 | — | — | US | disclosed |
| US-20110243849-A1 | HEME-BINDING PHOTOACTIVE POLYPEPTIDES AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-10-06 | — | — | US | disclosed |
| US-7888095-B2 | variant terpene cyclases; preferentially produces a sesquiterpene, using farnesyl diphosphate (FPP) as substrate | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-02-15 | — | — | US | disclosed |
| EP-1140089-A1 | LIPOSOMIC NIFLUMIC ACID - NEW TRANSDERMAL ANTI-INFLAMMATORY MEDICINE | P.N. GEROLYMATOS S.A. (GR) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000038681-A1 | LIPOSOMIC NIFLUMIC ACID - NEW TRANSDERMAL ANTI-INFLAMMATORY MEDICINE | P.N. GEROLYMATOS S.A. (GR) | 2000-07-06 | — | — | WO | disclosed |