Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL164218 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1KMT2AMEN1KEAP1 | |
| SCHEMBL1253282 | 0.95 | KDM4E (0.66) | KDM4EALDH1A1KMT2AMEN1KEAP1 | |
| SCHEMBL555454 | 0.95 | KDM4E (0.66) | KDM4EALDH1A1KMT2AMEN1KEAP1 | |
| SCHEMBL207631 | 0.92 | ALDH1A1 (0.44) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8646445 | 0.92 | KEAP1 (0.48) | KDM4EALDH1A1KMT2AMEN1KEAP1 | |
| SCHEMBL2411125 | 0.88 | KEAP1 (0.52) | KDM4EALDH1A1KMT2AMEN1KEAP1 | |
| SCHEMBL15732 | 0.88 | KEAP1 (0.52) | KDM4EALDH1A1KMT2AMEN1KEAP1 | |
| SCHEMBL98490 | 0.88 | ALDH1A1 (0.47) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1170638 | 0.86 | ALDH1A1 (0.42) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9493022 | 0.86 | ALDH1A1 (0.45) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9416416-B2 | Biological specimen collection/transport compositions and methods | LONGHORN VACCINES AND DIAGNOSTICS, LLC (US) | 2016-08-16 | — | — | US | disclosed |
| US-8618056-B2 | Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries | VIVACELLE BIO, INC. | 2013-12-31 | — | — | US | disclosed |
| US-20120087956-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS RELATED TO LACK OF BLOOD SUPPLY, SHOCK AND NEURONAL INJURIES | VIVACELLE BIO, INC. | 2012-04-12 | — | — | US | disclosed |
| US-20120028235-A1 | RESUSCITATION FLUID | VIVACELLE BIO, INC. | 2012-02-02 | — | — | US | disclosed |
| EP-0815081-B1 | PIPERIDINYL-2-ALKYL SUBSTITUTED LINEAR POLYAMINES FOR THE REDUCTION OF INTRACELLULAR, ENDOGENIC POLYAMINE LEVELS SUCH AS PUTRESCINE, SPERMIDINE AND SPERMINE, AND THEIR IMPACT ON CELL PROLIFERATION | NOVARTIS AG (CH) | 2001-10-04 | — | — | EP | disclosed |
| US-5834486-A | ANTIPROLIFERATIVE, ANTIPROTOZOA AGENTS | NOVARTIS AG (CH) | 1998-11-10 | — | — | US | disclosed |
| EP-0686143-B1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA GEIGY AG (CH) | 1998-08-12 | — | — | EP | disclosed |
| US-5627215-A | Unsaturate amino compounds for use as anticancer and antiprotozoic agent | CIBA-GEIGY CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0686143-A1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | Novartis AG (CH) | 1995-12-13 | — | — | EP | disclosed |
| WO-1995018091-A1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA-GEIGY AG (CH) | 1995-07-06 | — | — | WO | disclosed |