Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PTAFR | P25105 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87099 | 0.89 | PTAFR (0.44) | DNMT1RAD52UHRF1PIK3CBPIK3CG | |
| SCHEMBL86871 | 0.88 | PIK3CB (0.46) | DNMT1RAD52UHRF1PIK3CBPIK3CG | |
| SCHEMBL86842 | 0.87 | MEN1 (0.39) | DNMT1RAD52UHRF1PIK3CBPIK3CG | |
| SCHEMBL87126 | 0.87 | KCNK3 (0.43) | DNMT1RAD52UHRF1PIK3CBPIK3CG | |
| SCHEMBL86725 | 0.87 | MEN1 (0.41) | DNMT1RAD52UHRF1PIK3CBPIK3CG | |
| SCHEMBL86942 | 0.86 | NPC1 (0.44) | PTAFRKDM4EMEN1KMT2AMAPT | |
| SCHEMBL87360 | 0.86 | TDP1 (0.44) | DNMT1RAD52UHRF1PTAFRKDM4E | |
| SCHEMBL87108 | 0.86 | GAA (0.47) | PTAFRKDM4EMEN1KMT2AMAPT | |
| SCHEMBL86952 | 0.86 | ABCG2 (0.41) | DNMT1RAD52UHRF1PIK3CBPIK3CG | |
| SCHEMBL86960 | 0.85 | HCAR3 (0.40) | DNMT1RAD52UHRF1PIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042504-B1 | Fused azole-pyrimidine derivatives | BAYER SCHERING PHARMA AG (DE) | 2011-06-01 | — | — | EP | disclosed |