SCHEMBL12534530

SCHEMBL12534530

C=C(C)C(=O)N(CCCC)OC

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA9 Q16790 2/20 0.35
ALDH1A1 P00352 2/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP8 P22894 1/20 0.33
CES1 P23141 1/20 0.30
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12534539 0.90 ALDH1A1 (0.36) TSHRALDH1A1
SCHEMBL12534540 0.88 ALDH1A1 (0.34) TSHRALDH1A1
SCHEMBL17350333 0.88 ALDH1A1 (0.34) TSHRCA12CA9ALDH1A1THRB
SCHEMBL17350227 0.83 TSHR (0.38) TSHRCA12CA1CA9ALDH1A1
SCHEMBL12534527 0.79 ALDH1A1 (0.37) TSHRALDH1A1THRB
SCHEMBL18665383 0.79 CA1 (0.40) CA12CA1CA9ALDH1A1MMP1
SCHEMBL27543532 0.79 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL12534563 0.78 APP (0.31)
SCHEMBL12723949 0.78
SCHEMBL27543521 0.78 TSHR (0.45) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2960314-B1 POLISHING COMPOSITION AND METHOD FOR MANUFACTURING POLISHED ARTICLE FUJIMI INC (JP) 2024-06-26 EP disclosed
EP-3159915-B1 METHOD FOR POLISHING SILICON WAFER, POLISHING COMPOSITION, AND POLISHING COMPOSITION SET FUJIMI INC (JP) 2023-12-06 EP disclosed
CN-110462797-B Polishing composition 福吉米株式会社 2023-09-22 CN disclosed
EP-3133638-B1 COMPOSITION FOR POLISHING SILICON WAFERS FUJIMI INC (JP) 2021-10-27 EP disclosed
EP-2957613-B1 POLISHING COMPOSITION, METHOD FOR PRODUCING POLISHING COMPOSITION AND METHOD FOR PRODUCING POLISHED ARTICLE FUJIMI INC (JP) 2020-11-18 EP disclosed
US-10745588-B2 Silicon wafer polishing composition FUJIMI INCORPORATED (JP) 2020-08-18 US disclosed
EP-3007213-B1 USE OF A COMPOSITION FOR SILICON WAFER POLISHING FUJIMI INC (JP) 2020-03-18 EP disclosed
EP-3605588-A1 POLISHING COMPOSITION Fujimi Incorporated (JP) 2020-02-05 EP disclosed
CN-110320747-A CURABLE RESIN COMPOSITION, DRY FILM, CURED PRODUCT, AND PRINTED WIRING BOARD 太阳油墨制造株式会社 2019-10-11 CN disclosed
EP-3133639-B1 COMPOSITION FOR POLISHING SILICON WAFERS FUJIMI INC (JP) 2019-06-26 EP disclosed
US-8883877-B2 Materials based on radically polymerizable N,O-functionalized acrylic acid hydroxamides IVOCLAR VIVADENT AG (LI) 2014-11-11 US disclosed
US-8883877-B2 Materials based on radically polymerizable N,O-functionalized acrylic acid hydroxamides IVOCLAR VIVADENT AG (LI) 2014-11-11 US disclosed
US-20110130486-A1 Materials Based on Radically Polymerizable N,O-Functionalized Acrylic Acid Hydroxamides IVOCLAR VIVADENT AG (LI) 2011-06-02 US disclosed
US-20110130486-A1 Materials Based on Radically Polymerizable N,O-Functionalized Acrylic Acid Hydroxamides IVOCLAR VIVADENT AG (LI) 2011-06-02 US disclosed
US-7932303-B2 Materials based on radically polymerizable N,O-functionalized acrylic acid hydroxamides IVOCLAR VIVADENT AG (LI) 2011-04-26 US disclosed
US-7932303-B2 Materials based on radically polymerizable N,O-functionalized acrylic acid hydroxamides IVOCLAR VIVADENT AG (LI) 2011-04-26 US disclosed
EP-1974712-B1 Dental material based on radically polymerisable N,O-functionalised acrylic acid hydroxamides IVOCLAR VIVADENT AG (LI) 2010-10-27 EP disclosed
EP-1974712-A1 Dental material based on radically polymerisable N,O-functionalised acrylic acid hydroxamides Ivoclar Vivadent AG (LI) 2008-10-01 EP disclosed
US-20080234405-A1 very quickly cured; particularly suitable for dental purposes IVOCLAR VIVADENT AG (LI) 2008-09-25 US disclosed
US-20080234405-A1 very quickly cured; particularly suitable for dental purposes IVOCLAR VIVADENT AG (LI) 2008-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130486-A1 Materials Based on Radically Polymerizable N,O-Functionalized Acrylic Acid Hydroxamides H1-0, H1-2, H1-3 TSHR 4070/4885CA12 580/4885CA1 168/4885
US-20080234405-A1 very quickly cured; particularly suitable for dental purposes HRH4, HRH2, HRH3 TSHR 3656/4885CA12 327/4885CA1 140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.