SCHEMBL12536633

SCHEMBL12536633

COC(=O)c1ccc(OC(=O)c2cc(CO)c(CO)cc2OC)cc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.53
ALDH1A1 P00352 2/20 0.51
MAPT P10636 6/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
MEN1 O00255 3/20 0.45
ACR P10323 2/20 0.45
HGFAC Q04756 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KDM4E B2RXH2 3/20 0.44
PRSS1 P07477 1/20 0.44
POLB P06746 1/20 0.44
NPC1 O15118 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13121209 0.93 KMT2A (0.52) KMT2AALDH1A1MAPTCA1CA2
SCHEMBL12536643 0.88 KMT2A (0.55) KMT2AALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL17431105 0.86 KMT2A (0.48) KMT2AALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL12536657 0.86 KMT2A (0.49) KMT2AALDH1A1MAPTLMNAMEN1
SCHEMBL9905854 0.85 KMT2A (0.60) KMT2AALDH1A1MAPTCA1CA2
SCHEMBL12536634 0.84 NPSR1 (0.48) KMT2AALDH1A1MAPTMEN1POLB
SCHEMBL12536625 0.84 KMT2A (0.48) KMT2AALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL12536640 0.84 POLB (0.49) KMT2AALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL12536698 0.84 ALDH1A1 (0.48) KMT2AALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL12536683 0.83 KMT2A (0.47) KMT2AALDH1A1MAPTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8395727-B2 VA mode liquid crystal display device FUJIFILM CORPORATION (JP) 2013-03-12 US disclosed
US-20110128478-A1 POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD OF MANUFACTURING PROTECTIVE FILM FOR POLARIZING PLATE KONICA MINOLTA OPTO, INC. (JP) 2011-06-02 US disclosed
US-20110128473-A1 VA MODE LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-06-02 US disclosed