Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 13/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12536501 | 0.85 | CXCR3 (0.48) | CXCR3PDE10AMEN1KMT2A | |
| SCHEMBL12463991 | 0.84 | CXCR3 (0.55) | CXCR3LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL12463993 | 0.76 | CXCR3 (0.65) | CXCR3PDE10AMEN1KMT2A | |
| SCHEMBL12463668 | 0.75 | CXCR3 (0.56) | CXCR3PDE10AMEN1KMT2A | |
| SCHEMBL12464002 | 0.73 | CXCR3 (0.50) | CXCR3PDE10ALMNASMN1; SMN2MEN1 | |
| SCHEMBL12464100 | 0.73 | CXCR3 (0.67) | CXCR3 | |
| SCHEMBL13633678 | 0.73 | CXCR3 (0.66) | CXCR3 | |
| SCHEMBL12829869 | 0.72 | CXCR3 (0.56) | CXCR3 | |
| SCHEMBL16152253 | 0.71 | CXCR3 (0.58) | CXCR3PDE10A | |
| SCHEMBL449210 | 0.71 | CXCR3 (0.59) | CXCR3PDE10ALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2329822-A1 | Compositions and methods of treatment of cancer | Minerva Biotechnologies Corporation (US) | 2011-06-08 | — | — | EP | disclosed |