Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 6/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15039592 | 1.00 | KDM1A (0.43) | KDM1AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL859148 | 0.90 | CHRM5 (0.44) | KDM1AKDM4EGAAMEN1KMT2A | |
| SCHEMBL29394965 | 0.90 | CHRM5 (0.44) | KDM1AKDM4EGAAMEN1KMT2A | |
| SCHEMBL1051987 | 0.90 | CHRM5 (0.44) | KDM1AKDM4EGAAMEN1KMT2A | |
| SCHEMBL29589462 | 0.90 | CHRM5 (0.44) | KDM1AKDM4EGAAMEN1KMT2A | |
| SCHEMBL839974 | 0.90 | CHRM5 (0.44) | KDM1AKDM4EGAAMEN1KMT2A | |
| SCHEMBL30824576 | 0.90 | CHRM5 (0.44) | KDM1AKDM4EGAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL839730 | 0.88 | CHRM5 (0.43) | KDM1AKDM4EGAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL839085 | 0.88 | CHRM5 (0.43) | KDM1AKDM4EGAAMEN1KMT2A | |
| SCHEMBL1764675 | 0.84 | KDM4E (0.46) | KDM1AKDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136814-A1 | Diazepine and Diazocane Compounds As MC4 Agonists | ANDREWS MARK DAVID | 2011-06-09 | — | — | US | disclosed |
| US-20110136814-A1 | Diazepine and Diazocane Compounds As MC4 Agonists | ANDREWS MARK DAVID | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136814-A1 | Diazepine and Diazocane Compounds As MC4 Agonists | MC4R, CHRM4, GPR4 | KDM1A 1363/4885HTR1A 125/4885SLC6A2 1320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.