Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1883358 | 1.00 | — | — | |
| Bicarbonate SCHEMBL18787581 | 1.00 | — | — | |
| Bicarbonate SCHEMBL28045640 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL60565 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28131438 | 0.89 | CA1 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8206114 | 0.88 | — | — | |
| Bicarbonate SCHEMBL2346007 | 0.88 | CA4 (0.60) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL10394676 | 0.88 | — | — | |
| Bicarbonate SCHEMBL2237794 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1996859 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392432-B2 | Method for making a high surface area, small crystallite size catalyst for Fischer-Tropsch synthesis | CLARIANT CORP (US) | 2019-12-25 | — | — | EP | claimed |
| EP-1392432-B1 | Method for making a high surface area, small crystallite size catalyst for Fischer-Tropsch synthesis | SUED CHEMIE INC (US) | 2012-07-11 | — | — | EP | claimed |
| EP-2286913-A2 | High surface area, small crystallite size catalyst for Fischer-Tropsch | Süd-Chemie Inc. (US) | 2011-02-23 | — | — | EP | claimed |
| EP-1392432-B2 | Method for making a high surface area, small crystallite size catalyst for Fischer-Tropsch synthesis | CLARIANT CORP (US) | 2019-12-25 | — | — | EP | disclosed |
| EP-1392432-B1 | Method for making a high surface area, small crystallite size catalyst for Fischer-Tropsch synthesis | SUED CHEMIE INC (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-2286913-A2 | High surface area, small crystallite size catalyst for Fischer-Tropsch | Süd-Chemie Inc. (US) | 2011-02-23 | — | — | EP | disclosed |
| US-7585812-B2 | Transition metal-based catalyst having a high surface area, a smooth, homogeneous surface morphology, uniform distribution of cobalt throughout the support, and a small metal crystallite size; smooth, homogeneous surface morphology; decompoisiton of metal salt in a carrier, calcination, reduction | SUD-CHEMIE INC. (US) | 2009-09-08 | — | — | US | disclosed |
| US-20090036296-A1 | High surface area, small crystallite size catalyst for Fischer-Tropsch synthesis | CLARIANT INTERNATIONAL LTD. (CH) | 2009-02-05 | — | — | US | disclosed |
| US-7452844-B2 | High surface area, small crystallite size catalyst for Fischer-Tropsch synthesis | Süd-Chemie Inc (US) | 2008-11-18 | — | — | US | disclosed |
| US-20070099797-A1 | High surface area, small crystallite size catalyst for fischer-tropsch synthesis | CLARIANT INTERNATIONAL LTD. (CH) | 2007-05-03 | — | — | US | disclosed |
| EP-1392432-A4 | HIGH SURFACE AREA, SMALL CRYSTALLITE SIZE CATALYST FOR FISCHER-TROPSCH SYNTHESIS | SUED CHEMIE INC (US) | 2006-03-01 | — | — | EP | disclosed |
| EP-1392432-A1 | HIGH SURFACE AREA, SMALL CRYSTALLITE SIZE CATALYST FOR FISCHER-TROPSCH SYNTHESIS | Süd-Chemie, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002089978-A1 | HIGH SURFACE AREA, SMALL CRYSTALLITE SIZE CATALYST FOR FISCHER-TROPSCH SYNTHESIS | SUD-CHEMIE, INC. (US) | 2002-11-14 | — | — | WO | disclosed |