Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.60 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7170334 | 0.94 | CA4 (0.70) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL28045640 | 0.94 | CA4 (0.50) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL60565 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28420909 | 0.94 | CA4 (0.67) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL2275798 | 0.94 | CA4 (0.67) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL1332143 | 0.94 | — | — | |
| Bicarbonate SCHEMBL2351948 | 0.94 | CA4 (0.67) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL852 | 0.94 | — | — | |
| Bicarbonate SCHEMBL19379543 | 0.89 | CA4 (0.50) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL23246204 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1637562-B1 | ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING SAME | DAINIPPON INK & CHEMICALS (JP) | 2011-08-31 | — | — | EP | disclosed |
| US-7652088-B2 | Organic-inorganic composite material and method for producing the same | DIC CORPORATION (JP) | 2010-01-26 | — | — | US | disclosed |
| US-7630116-B2 | Ion conductor and electrochemical display device utilizing the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20090168141-A1 | Electrolytic solution impregnated in polymer particle formed via interfacial polycondensation | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2009-07-02 | — | — | US | disclosed |
| US-20070293615-A1 | Organic-Inorganic Composite Material and Method for Producing the Same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-12-20 | — | — | US | disclosed |
| EP-1715493-A1 | ION CONDUCTOR AND ELECTROCHEMICAL DISPLAY DEVICE UTILIZING THE SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-10-25 | — | — | EP | disclosed |
| EP-1637562-A9 | ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-10-11 | — | — | EP | disclosed |
| EP-1637562-A1 | ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-03-22 | — | — | EP | disclosed |