Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12539679 | 1.00 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL1947311 | 1.00 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL1943610 | 1.00 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| Hydrochloric Acid SCHEMBL1956488 | 0.98 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL1945058 | 0.91 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL1945093 | 0.87 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL20052872 | 0.85 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL17455406 | 0.85 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL12574956 | 0.83 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL1945059 | 0.82 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136787-A1 | DIPHENYL AZEPANE, DIAZEPANE AND OXAZEPANE DERIVATIVES AND USES THEREOF | SCHOENFELD RYAN CRAIG | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136787-A1 | DIPHENYL AZEPANE, DIAZEPANE AND OXAZEPANE DERIVATIVES AND USES THEREOF | PTGDR2, PTGDR, TBXA2R | SLC6A2 2364/4885SLC6A4 2007/4885SLC6A3 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.