Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 11/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 7/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17455406 | 1.00 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL14739080 | 0.85 | SLC6A4 (0.74) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL14739638 | 0.85 | SLC6A4 (0.74) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL14739408 | 0.85 | SLC6A4 (0.74) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL14738866 | 0.85 | SLC6A4 (0.74) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL3666071 | 0.85 | SLC6A4 (0.74) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL1947311 | 0.85 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL1943610 | 0.85 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL12539679 | 0.85 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL12539616 | 0.85 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944618-B2 | Inhibiting neurotransmitter reuptake | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2018-04-17 | — | — | US | disclosed |