Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.65 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174249 | 1.00 | SIGMAR1 (0.65) | SIGMAR1TAAR1SLC18A2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL219711 | 0.98 | SIGMAR1 (0.63) | SIGMAR1TAAR1SLC18A2NPC1RAB9A | |
| Iodide SCHEMBL221293 | 0.98 | SIGMAR1 (0.63) | SIGMAR1TAAR1SLC18A2NPC1RAB9A | |
| Bromide SCHEMBL221648 | 0.98 | SIGMAR1 (0.63) | SIGMAR1TAAR1SLC18A2NPC1RAB9A | |
| Hydroxyamphetamine SCHEMBL7041719 | 0.83 | TAAR1 (0.66) | SIGMAR1TAAR1SLC18A2SLC6A4 | |
| SCHEMBL30624762 | 0.81 | SIGMAR1 (0.71) | SIGMAR1TAAR1SLC18A2NPC1RAB9A | |
| SCHEMBL21243273 | 0.81 | SIGMAR1 (0.73) | SIGMAR1TAAR1SLC18A2NPC1RAB9A | |
| SCHEMBL2958028 | 0.80 | SLC6A4 (0.63) | SIGMAR1TAAR1SLC6A4CYP3A4CYP2D6 | |
| Methamphetamine SCHEMBL18227057 | 0.80 | SIGMAR1 (0.91) | SIGMAR1TAAR1SLC18A2NPC1RAB9A | |
| Methamphetamine SCHEMBL42615 | 0.79 | SIGMAR1 (1.00) | SIGMAR1TAAR1SLC18A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2852 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12605345-B2 | Transdermal drug delivery system | BioPhysics Pharma, Inc. (US) | 2026-04-21 | — | — | US | claimed |
| EP-3870170-B1 | TREATMENT OF PRESBYOPIA AND MYDRIASIS WITH PHENTOLAMINE | OPUS GENETICS INC (US) | 2026-02-25 | — | — | EP | claimed |
| US-20260027139-A1 | TREATMENT OF SLEEP APNEA WITH A COMBINATION OF A CARBONIC ANHYDRASE INHIBITOR AND AN ALDOSTERONE ANTAGONIST | VIVUS, INC. | 2026-01-29 | — | — | US | claimed |
| US-20250213647-A1 | CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE | UNIVERSITY OF SOUTH FLORIDA | 2025-07-03 | — | — | US | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| US-20240415738-A1 | DEVICES AND METHODS FOR CORNEA TREATMENT | D&D Biopharmaceuticals, Inc. (US) | 2024-12-19 | — | — | US | claimed |
| EP-3413872-B1 | NON-INVASIVE OCULAR DRUG DELIVERY INSERT TECHNOLOGY | UNIV DE COIMBRA (PT) | 2024-10-02 | — | — | EP | claimed |
| WO-2024163315-A2 | DERIVATIZED COLLAGEN-HYALURONIC ACID BASED IMPLANTS FOR SUSTAINED DELIVERY OF OPHTHALMIC DRUGS | DEVORE DALE (US) | 2024-08-08 | — | — | WO | claimed |
| US-20240252446-A1 | DERIVATIZED COLLAGEN-HYALURONIC ACID BASED IMPLANTS FOR SUSTAINED DELIVERY OF OPHTHALMIC DRUGS | SUSTAINED DRUG DELIVERY LLC | 2024-08-01 | — | — | US | claimed |
| US-20240216334-A1 | METHODS AND COMPOSITIONS FOR TREATING MYDRIASIS, GLAUCOMA, AND OTHER OCULARCONDITIONS | OPUS GENETICS, INC. | 2024-07-04 | — | — | US | claimed |
| EP-0745391-A1 | Apparatus, method and composition for preserving media in tip of solution dispenser | CIBA-GEIGY AG (CH) | 1996-12-04 | — | — | EP | claimed |
| EP-0126684-B1 | DRUG DELIVERY SYSTEM UTILIZING THERMOSETTING GELS | MERCK & CO. INC. (US) | 1991-08-28 | — | — | EP | claimed |
| EP-0046270-B1 | NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | INTERx RESEARCH CORPORATION (US) | 1986-05-21 | — | — | EP | claimed |
| EP-0152379-A2 | Process for preparing pharmaceutical compositions containing unilamellar liposomes | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | claimed |
| EP-0126684-A2 | Drug delivery system utilizing thermosetting gels | MERCK & CO. INC. (US) | 1984-11-28 | — | — | EP | claimed |
| US-4474751-A | SUSTAINED RELEASE USING AN ALKYLENEDIAMINE-MODIFIED ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER | MERCK & CO., INC. (US) | 1984-10-02 | — | — | US | claimed |
| EP-0059057-A1 | Treatment of diarrhoea | BEECHAM GROUP PLC (GB) | 1982-09-01 | — | — | EP | claimed |
| EP-0046270-A1 | Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them | INTERx RESEARCH CORPORATION (US) | 1982-02-24 | — | — | EP | claimed |
| US-4186184-A | Selective administration of drug with ocular therapeutic system | ALZA CORPORATION (US) | 1980-01-29 | — | — | US | claimed |
| US-3968245-A | Sympathomimetic topical and percutaneous administration with halogenated promoters | ALZA CORPORATION (US) | 1976-07-06 | — | — | US | claimed |