SCHEMBL1254564

SCHEMBL1254564

CCCCCCCCSSSSCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
THRB P10828 2/20 0.50
HSD17B10 Q99714 2/20 0.41
CES2 O00748 1/20 0.41
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
GMNN O75496 1/20 0.41
TP53 P04637 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
BLM P54132 1/20 0.41
CA2 P00918 1/20 0.39
DNM1 Q05193 7/20 0.39
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
SLC22A1 O15245 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3519539 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL1254576 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL1255801 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL1253219 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL17748758 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL3519329 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL3518328 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL3521290 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL1163997 0.97 TSHR (0.47) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL11859128 0.97 TSHR (0.47) TSHRTHRBHSD17B10CES2CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12516193-B2 Rubber-modified bitumen, process for production thereof and use thereof in asphalt LANXESS DEUTSCHLAND GMBH (DE) 2026-01-06 US claimed
CN-114207048-B Rubber-modified asphalt, method for the production thereof and use thereof in asphalt 朗盛德国有限责任公司 2023-05-05 CN claimed
US-20220275211-A1 Rubber-Modified Bitumen, Process for Production Thereof and Use Thereof in Asphalt LANXESS DEUTSCHLAND GMBH (DE) 2022-09-01 US claimed
EP-4007794-A1 RUBBER-MODIFIED BITUMENS, METHOD OF PRODUCTION AND USE THEREOF IN ASPHALT LANXESS Deutschland GmbH (DE) 2022-06-08 EP claimed
EP-3771727-B1 RUBBER-MODIFIED BITUMEN, METHOD FOR ITS PREPARATION AND ITS USE IN ASPHALT LANXESS DEUTSCHLAND GMBH (DE) 2022-03-23 EP claimed
CN-114207048-A Rubber-modified bitumen, method for the production thereof and use thereof in asphalt 朗盛德国有限责任公司 2022-03-18 CN claimed
WO-2021018892-A1 RUBBER-MODIFIED BITUMENS, METHOD OF PRODUCTION AND USE THEREOF IN ASPHALT LANXESS DEUTSCHLAND GMBH (DE) 2021-02-04 WO claimed
EP-3771727-A1 RUBBER-MODIFIED BITUMEN, METHOD FOR ITS PREPARATION AND ITS USE IN ASPHALT LANXESS Deutschland GmbH (DE) 2021-02-03 EP claimed
US-10844190-B2 Method for producing rubber-modified bitumen using vulcanized rubber LANXESS DEUTSCHLAND GMBH (DE) 2020-11-24 US claimed
CN-108137860-B Process for producing rubber-modified asphalt using vulcanized rubber 朗盛德国有限责任公司 2019-12-20 CN claimed
EP-2955202-A1 Method for improving adhesion between bitumen and stone in asphalt Rhein Chemie Rheinau GmbH (DE) 2015-12-16 EP claimed
EP-2164895-B1 METHOD FOR THE REGENERATION OF RUBBERS RHEIN CHEMIE RHEINAU GMBH (DE) 2015-02-25 EP claimed
EP-2395046-A1 New method for producing rubber-modified bitumen from vulcanized rubber Rhein Chemie Rheinau GmbH (DE) 2011-12-14 EP claimed
WO-2011138412-A1 NOVEL METHOD FOR PRODUCING RUBBER-MODIFIED BITUMEN FROM VULCANIZED RUBBER RHEIN CHEMIE RHEINAU GMBH (DE) 2011-11-10 WO claimed
US-RE42165-E1 Modified asphalt compositions WESTLAKE LONGVIEW CORP. (US) 2011-02-22 US claimed
CN-101688014-A Be used for method to regeneration of rubbers RHEIN CHEMIE RHEINAU GMBH 2010-03-31 CN claimed
EP-2164895-A1 METHOD FOR THE REGENERATION OF RUBBERS Rhein Chemie Rheinau GmbH (DE) 2010-03-24 EP claimed
WO-2008148706-A1 METHOD FOR THE REGENERATION OF RUBBERS RHEIN CHEMIE RHEINAU GMBH (DE) 2008-12-11 WO claimed
US-7202290-B2 Modified asphalt compositions EASTMAN CHEMICAL COMPANY (US) 2007-04-10 US claimed
US-20050101702-A1 mixtures of oxidized polyethylene, styrene-butadiene-styrene block copolymer and asphalt having storage stability and good workability, used as pavings BARINGS FINANCE LLC, AS ADMINISTRATIVE AGENT 2005-05-12 US claimed