SCHEMBL1254576

SCHEMBL1254576

CCCCCCCCCSSSSCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
THRB P10828 2/20 0.50
HSD17B10 Q99714 2/20 0.41
CES2 O00748 1/20 0.41
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
GMNN O75496 1/20 0.41
TP53 P04637 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
BLM P54132 1/20 0.41
CA2 P00918 1/20 0.39
DNM1 Q05193 7/20 0.39
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
SLC22A1 O15245 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1254564 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL3519539 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL1255801 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL1253219 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL17748758 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL3519329 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL3518328 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL3521290 1.00 TSHR (0.50) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL1163997 0.97 TSHR (0.47) TSHRTHRBHSD17B10CES2CTSL
SCHEMBL11859128 0.97 TSHR (0.47) TSHRTHRBHSD17B10CES2CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE42165-E1 Modified asphalt compositions WESTLAKE LONGVIEW CORP. (US) 2011-02-22 US claimed
US-7202290-B2 Modified asphalt compositions EASTMAN CHEMICAL COMPANY (US) 2007-04-10 US claimed
US-20050101702-A1 mixtures of oxidized polyethylene, styrene-butadiene-styrene block copolymer and asphalt having storage stability and good workability, used as pavings BARINGS FINANCE LLC, AS ADMINISTRATIVE AGENT 2005-05-12 US claimed
US-5856609-A Aromatic hydrodealkylation process with sulfur oxide containing catalyst PHILLIPS PETROLEUM COMPANY (US) 1999-01-05 US claimed
WO-2024038177-A1 BITUMEN/POLYMER COMPOSITION WITH IMPROVED MECHANICAL PROPERTIES TOTALENERGIES ONETECH (FR) 2024-02-22 WO disclosed
EP-4324884-A1 BITUMEN/POLYMER COMPOSITION WITH IMPROVED MECHANICAL PROPERTIES TotalEnergies OneTech (FR) 2024-02-21 EP disclosed
WO-2024017872-A1 USE OF A HYDROXIDE FOR ADJUSTING THE ELASTIC PROPERTIES OF A CROSSLINKED ELASTOMER- MODIFIED BITUMEN TOTALENERGIES ONETECH (FR) 2024-01-25 WO disclosed
EP-4310152-A1 USE OF A HYDROXIDE FOR ADJUSTING THE ELASTIC PROPERTIES OF A CROSSLINKED ELASTOMER-MODIFIED BITUMEN TotalEnergies OneTech (FR) 2024-01-24 EP disclosed
WO-2023120360-A1 FISHING NET ANTIFOULING COATING COMPOSITION AND FISHING NET, FISHING NET GEAR, OR UNDERWATER STRUCTURE HAVING ON SURFACE THEREOF ANTIFOULING COATING FILM FORMED USING SAID COMPOSITION 日東化成株式会社 2023-06-29 WO disclosed
CN-102892838-B Organic gelling agent derivative in bituminous composition in order to improve the purposes of bituminous composition to the tolerance of chemical erosion TOTAL RAFFINAGE MARKETING (FR) 2015-11-25 CN disclosed
US-9150454-B2 Use of organogelator molecules in bituminous compositions to improve the resistance of same to chemical stress TOTAL RAFFINAGE MARKETING (FR) 2015-10-06 US disclosed
CN-102947242-B Use of organogelator molecules in bituminous compositions to improve the resistance of same to chemical stress TOTAL RAFFINAGE MARKETING 2015-07-22 CN disclosed
US-5763721-A CATALYST COMPRISED OF METAL OXIDE PROMOTED ALUMINA CONTAINING A SILICON OXIDE AND PHOSPHORUS OXIDE PHILLIPS PETROLEUM COMPANY (US) 1998-06-09 US disclosed
US-5750598-A Bitumen/polymer composition vulcanizable at temperatures below 100°C ELI FRANCE (FR) 1998-05-12 US disclosed
US-5585334-A Process for dissolving sulfur PHILLIPS PETROLEUM COMPANY (US) 1996-12-17 US disclosed
US-5382612-A Vulcanizing bitumen/elastomer mixture, road paving ELF FRANCE (FR) 1995-01-17 US disclosed
US-5314935-A Roadways ELF ANTAR FRANCE (FR) 1994-05-24 US disclosed
US-5120777-A Organonitrogen compound as coupler ELF FRANCE (FR) 1992-06-09 US disclosed
US-4567222-A POLYSULFIDE ELF FRANCE (FR) 1986-01-28 US disclosed
US-4554313-A Process for preparing bitumen-polymer compositions, application of these compositions of the obtention of coverings and mother solution of polymer usable for the obtention of the said compositions SOCIETE ANONYME DITE: ELF FRANCE (FR) 1985-11-19 US disclosed