⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140997 | 0.69 | DAO (0.41) | — | |
| SCHEMBL23491386 | 0.69 | — | — | |
| SCHEMBL4088962 | 0.69 | — | — | |
| SCHEMBL354088 | 0.69 | — | — | |
| SCHEMBL18701804 | 0.69 | — | — | |
| Ammonia Solution, Strong SCHEMBL23116686 | 0.69 | — | — | |
| SCHEMBL17964082 | 0.69 | — | — | |
| SCHEMBL4391479 | 0.69 | — | — | |
| SCHEMBL3924650 | 0.69 | — | — | |
| SCHEMBL5154615 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12351586-B2 | Thiophene[2,3-d]pyrimidine derivative DK6-1 and its preparation method and application | SHAN DONG UNIVERSITY (CN) | 2025-07-08 | — | — | US | claimed |
| CN-119361834-A | Electrolyte and battery and electricity utilization device containing same | 浙江大学 | 2025-01-24 | — | — | CN | claimed |
| CN-115340468-B | (R) -deuterated phenylalanine derivative and preparation method thereof | 西南大学 | 2023-10-24 | — | — | CN | claimed |
| CN-116178486-A | Asymmetric hydrogenation synthesis method and application of non-natural polypeptide | 西南大学 | 2023-05-30 | — | — | CN | claimed |
| US-20230067045-A1 | THIOPHENE[2,3-D]PYRIMIDINE DERIVATIVE DK6-1 AND ITS PREPARATION METHOD AND APPLICATION | SHAN DONG UNIVERSITY (CN) | 2023-03-02 | — | — | US | claimed |
| CN-115340468-A | (R) -deuterated phenylalanine derivative and preparation method thereof | 西南大学 | 2022-11-15 | — | — | CN | claimed |
| CN-106866699-B | A kind of diaryl thienopyrimidines HIV-1 reverse transcriptase inhibitor and its preparation method and application | 山东大学 | 2019-03-08 | — | — | CN | claimed |
| CN-108440559-A | Diaryl thienopyrimidines HIV-1 reverse transcriptase inhibitor and its preparation method and application | 山东大学 | 2018-08-24 | — | — | CN | claimed |
| CN-108358949-A | The preparation method of 2,4- of one kind dichloro-thiophenes simultaneously [3,2-D] pyrimidine | 南京法恩化学有限公司 | 2018-08-03 | — | — | CN | claimed |
| CN-106866699-A | A kind of RTIs of diaryl thienopyrimidines HIV 1 and its preparation method and application | 山东大学 | 2017-06-20 | — | — | CN | claimed |
| CN-104530078-B | Thieno [3, 2-d] pyrimidine derivative and preparation method and application thereof | 山东大学 | 2017-03-22 | — | — | CN | claimed |
| CN-102924473-B | The preparation method of the chloro-7-iodothiophen of a kind of 2-also [3,2-D] pyrimidine | SHANGHAI BEPHARM CO., LTD. (CN) | 2015-09-02 | — | — | CN | claimed |
| CN-104530078-A | Thieno [3, 2-d] pyrimidine derivative and preparation method and application thereof | UNIV SHANDONG | 2015-04-22 | — | — | CN | claimed |
| CN-102924473-A | Preparation method of 2-chlorine-7-iodothieno[3,2-D] pyrimidine | SHANGHAI BEPHARM CO LTD | 2013-02-13 | — | — | CN | claimed |
| US-12351586-B2 | Thiophene[2,3-d]pyrimidine derivative DK6-1 and its preparation method and application | SHAN DONG UNIVERSITY (CN) | 2025-07-08 | — | — | US | disclosed |
| CN-119798275-A | Preparation method of 2, 4-dichloro-thieno [3,2, d ] pyrimidine | 安徽尖峰北卡药业有限公司 | 2025-04-11 | — | — | CN | disclosed |
| US-12247004-B2 | 2-amino-N-(amino-oxo-aryl-lambda6-sulfanylidene)acetamide compounds and their therapeutic use | Oxford Drug Design Limited (GB) | 2025-03-11 | — | — | US | disclosed |
| WO-2002055524-A1 | THIENO(3,2-d)PYRIMIDINES AND FURANO(3,2-d)PYRIMIDINES AND THEIR USE AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RESEARCH LIMITED (GB) | 2002-07-18 | — | — | WO | disclosed |
| EP-0219797-A1 | Process for the preparation of 2,3-dichlorothiophene | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-29 | — | — | EP | disclosed |
| US-4350518-A | Plant growth regulating substituted alkylammonium salts | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |